Leishmania braziliensis prostaglandin F2α synthase impacts host infection

Leishmania braziliensis prostaglandin F2α synthase impacts host infection

Abstract Background Prostaglandins (PG) are lipid mediators derived from arachidonic acid metabolism. They are involved in cellular processes such as inflammation and tissue homeostasis. PG production is not restricted to multicellular organisms. Trypanosomatids also synthesize several metabolites o...

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Bibliographic Details
Main Authors: Eliza Vanessa Carneiro Alves-Ferreira, Tiago Rodrigues Ferreira, Pegine Walrad, Paul M. Kaye, Angela Kaysel Cruz
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Parasites & Vectors
Subjects:
Leishmania braziliensis
LbrPGF2S
Macrophage
Host-parasite
PGF2α
Online Access:https://doi.org/10.1186/s13071-020-3883-z

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