THE BASIC PRINCIPLES OF TREATMENT OF ANKYLOSING SPONDYLITIS (BECHTEREW'S DISEASE)

The history of treatment of ankylosing spondylitis (AS) and the reasons behind the development of modern approaches to its therapy are briefly described. The main tasks and principles of non-pharmacological and drug therapies for ASare briefly reported. The need for therapeutic physical training is...

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Main Author: Shandor Fedorovich Erdes
Format: Article
Language:Russian
Published: IMA PRESS LLC 2014-02-01
Series:Научно-практическая ревматология
Subjects:
Online Access:https://rsp.mediar-press.net/rsp/article/view/1353
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author Shandor Fedorovich Erdes
author_facet Shandor Fedorovich Erdes
author_sort Shandor Fedorovich Erdes
collection DOAJ
description The history of treatment of ankylosing spondylitis (AS) and the reasons behind the development of modern approaches to its therapy are briefly described. The main tasks and principles of non-pharmacological and drug therapies for ASare briefly reported. The need for therapeutic physical training is emphasized, since its role in maintaining the functional status in this group of patients has been proved. The lecture casts doubt on effectiveness of physiotherapy andother physical techniques because of the poor evidence base. The lecture emphasizes the disease-modifying role of nonsteroidal anti-inflammatory drugs and requirement to receive them constantly for patients with Bechterew's disease. Meanwhile, the basic anti-inflammatory drugs in patients with this disease are reported to play an auxiliary role and to have no effect on disease progression. The pronounced clinical effectiveness of all tumor necrosis factor α inhibitors is emphasized; certain differences in their therapeutical effect are described. The problems of surgical treatment, which deal with correction of disease complications or undesirable effects, are discussed.
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spelling doaj.art-ca0c76e1d23a43138e91951d2ea2af202023-03-22T13:45:49ZrusIMA PRESS LLCНаучно-практическая ревматология1995-44841995-44922014-02-015166869510.14412/1995-4484-2013-686-951293THE BASIC PRINCIPLES OF TREATMENT OF ANKYLOSING SPONDYLITIS (BECHTEREW'S DISEASE)Shandor Fedorovich Erdes0Nasonova Research Institute of Rheumatology, Russian Academy of Medical Sciences, Moscow, RussiaThe history of treatment of ankylosing spondylitis (AS) and the reasons behind the development of modern approaches to its therapy are briefly described. The main tasks and principles of non-pharmacological and drug therapies for ASare briefly reported. The need for therapeutic physical training is emphasized, since its role in maintaining the functional status in this group of patients has been proved. The lecture casts doubt on effectiveness of physiotherapy andother physical techniques because of the poor evidence base. The lecture emphasizes the disease-modifying role of nonsteroidal anti-inflammatory drugs and requirement to receive them constantly for patients with Bechterew's disease. Meanwhile, the basic anti-inflammatory drugs in patients with this disease are reported to play an auxiliary role and to have no effect on disease progression. The pronounced clinical effectiveness of all tumor necrosis factor α inhibitors is emphasized; certain differences in their therapeutical effect are described. The problems of surgical treatment, which deal with correction of disease complications or undesirable effects, are discussed.https://rsp.mediar-press.net/rsp/article/view/1353ankylosing spondylitistherapytumor necrosis factor α inhibitorstherapeutic physical training
spellingShingle Shandor Fedorovich Erdes
THE BASIC PRINCIPLES OF TREATMENT OF ANKYLOSING SPONDYLITIS (BECHTEREW'S DISEASE)
Научно-практическая ревматология
ankylosing spondylitis
therapy
tumor necrosis factor α inhibitors
therapeutic physical training
title THE BASIC PRINCIPLES OF TREATMENT OF ANKYLOSING SPONDYLITIS (BECHTEREW'S DISEASE)
title_full THE BASIC PRINCIPLES OF TREATMENT OF ANKYLOSING SPONDYLITIS (BECHTEREW'S DISEASE)
title_fullStr THE BASIC PRINCIPLES OF TREATMENT OF ANKYLOSING SPONDYLITIS (BECHTEREW'S DISEASE)
title_full_unstemmed THE BASIC PRINCIPLES OF TREATMENT OF ANKYLOSING SPONDYLITIS (BECHTEREW'S DISEASE)
title_short THE BASIC PRINCIPLES OF TREATMENT OF ANKYLOSING SPONDYLITIS (BECHTEREW'S DISEASE)
title_sort basic principles of treatment of ankylosing spondylitis bechterew s disease
topic ankylosing spondylitis
therapy
tumor necrosis factor α inhibitors
therapeutic physical training
url https://rsp.mediar-press.net/rsp/article/view/1353
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