Factors associated with breast cancer in Puerto Rican women
Background: Breast cancer (BC) is the most common cancer afflicting Puerto Rican women and accounts for more cancer-related deaths in this population than any other cancer. Methods: Demographic, anthropometric, family history, and lifestyle data, as well as DNA repair capacity (DRC), were compared...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Springer
2019-04-01
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| Series: | Journal of Epidemiology and Global Health |
| Subjects: | |
| Online Access: | https://www.atlantis-press.com/article/125905937/view |
| _version_ | 1818006909069819904 |
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| author | Luisa Morales Carolina Alvarez-Garriga Jaime Matta Carmen Ortiz Yeidyly Vergne Wanda Vargas Heidi Acosta Jonathan Ramírez Julyann Perez-Mayoral Manuel Bayona |
| author_facet | Luisa Morales Carolina Alvarez-Garriga Jaime Matta Carmen Ortiz Yeidyly Vergne Wanda Vargas Heidi Acosta Jonathan Ramírez Julyann Perez-Mayoral Manuel Bayona |
| author_sort | Luisa Morales |
| collection | DOAJ |
| description | Background: Breast cancer (BC) is the most common cancer afflicting Puerto Rican women and accounts for more cancer-related deaths in this population than any other cancer.
Methods: Demographic, anthropometric, family history, and lifestyle data, as well as DNA repair capacity (DRC), were compared in 465 BC cases and 661 controls. Crude and multiple logistic regression-derived adjusted odds ratios were used as indicators of the associations between BC and the variables under study.
Results: A low DRC level, aging (>61 years), family history of BC, and low education level had statistically significant associations with increased BC risk. Endometriosis, full-term pregnancy at an earlier age, higher parity, hysterectomy before age 50, multivitamin and calcium intake, and longer duration of breastfeeding significantly decreased BC risk.
Conclusions: This study discusses the major risk factors for BC in Puerto Rico (PR). Because many of these findings represent modifiable risk factors, they can translate into public health initiatives to lower BC risk. In addition, the possibility of using DRC as a simple screening tool for BC risk is explored. |
| first_indexed | 2024-04-14T05:07:54Z |
| format | Article |
| id | doaj.art-ca0ddd8501dc46678a751aa57d08c990 |
| institution | Directory Open Access Journal |
| issn | 2210-6006 |
| language | English |
| last_indexed | 2024-04-14T05:07:54Z |
| publishDate | 2019-04-01 |
| publisher | Springer |
| record_format | Article |
| series | Journal of Epidemiology and Global Health |
| spelling | doaj.art-ca0ddd8501dc46678a751aa57d08c9902022-12-22T02:10:39ZengSpringerJournal of Epidemiology and Global Health2210-60062019-04-013410.1016/j.jegh.2013.08.003Factors associated with breast cancer in Puerto Rican womenLuisa MoralesCarolina Alvarez-GarrigaJaime MattaCarmen OrtizYeidyly VergneWanda VargasHeidi AcostaJonathan RamírezJulyann Perez-MayoralManuel BayonaBackground: Breast cancer (BC) is the most common cancer afflicting Puerto Rican women and accounts for more cancer-related deaths in this population than any other cancer. Methods: Demographic, anthropometric, family history, and lifestyle data, as well as DNA repair capacity (DRC), were compared in 465 BC cases and 661 controls. Crude and multiple logistic regression-derived adjusted odds ratios were used as indicators of the associations between BC and the variables under study. Results: A low DRC level, aging (>61 years), family history of BC, and low education level had statistically significant associations with increased BC risk. Endometriosis, full-term pregnancy at an earlier age, higher parity, hysterectomy before age 50, multivitamin and calcium intake, and longer duration of breastfeeding significantly decreased BC risk. Conclusions: This study discusses the major risk factors for BC in Puerto Rico (PR). Because many of these findings represent modifiable risk factors, they can translate into public health initiatives to lower BC risk. In addition, the possibility of using DRC as a simple screening tool for BC risk is explored.https://www.atlantis-press.com/article/125905937/viewBreast cancerEpidemiologyRisk factorsProtective factorsDNA repair capacityReceptor status |
| spellingShingle | Luisa Morales Carolina Alvarez-Garriga Jaime Matta Carmen Ortiz Yeidyly Vergne Wanda Vargas Heidi Acosta Jonathan Ramírez Julyann Perez-Mayoral Manuel Bayona Factors associated with breast cancer in Puerto Rican women Journal of Epidemiology and Global Health Breast cancer Epidemiology Risk factors Protective factors DNA repair capacity Receptor status |
| title | Factors associated with breast cancer in Puerto Rican women |
| title_full | Factors associated with breast cancer in Puerto Rican women |
| title_fullStr | Factors associated with breast cancer in Puerto Rican women |
| title_full_unstemmed | Factors associated with breast cancer in Puerto Rican women |
| title_short | Factors associated with breast cancer in Puerto Rican women |
| title_sort | factors associated with breast cancer in puerto rican women |
| topic | Breast cancer Epidemiology Risk factors Protective factors DNA repair capacity Receptor status |
| url | https://www.atlantis-press.com/article/125905937/view |
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