Polygenic Risk Score Predicts Earlier-Onset Adult Systemic Lupus Erythematosus and First-Year Renal Diseases in a Taiwanese Cohort

Polygenic Risk Score Predicts Earlier-Onset Adult Systemic Lupus Erythematosus and First-Year Renal Diseases in a Taiwanese Cohort

Objectives This study aimed to develop a predictive model using polygenic risk score (PRS) to forecast renal outcomes for adult systemic lupus erythematosus (SLE) in a Taiwanese population.Methods Patients with SLE (n=2782) and matched non-SLE controls (n=11 128) were genotyped using Genome-Wide TWB...

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Main Authors: Yi-Ming Chen, Ching-Heng Lin, Wen-Juei Jeng, Hwai-I Yang, Yen-Ju Chen, Tzu-Hung Hsiao, Ying-Cheng Lin, Chien-Lin Mao, Chia-Yi Wei, Yi-Chung Hsieh, Chih-Jen Huang, Mei-Hung Pan, I-Chieh Chen
Format: Article
Language:English
Published: BMJ Publishing Group 2024-04-01
Series:RMD Open
Online Access:https://rmdopen.bmj.com/content/10/2/e003293.full

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https://rmdopen.bmj.com/content/10/2/e003293.full

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