Nickel-Imidazolium Low Transition Temperature Mixtures with Lewis-Acidic Character
Low transition temperature mixtures (LTTMs) are a new generation of solvents that have found extensive application in organic synthesis. The interactions between the components often generate highly activated, catalytically active species, thus opening the possibility of using LTTMs as catalysts, ra...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-08-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/28/17/6338 |
| _version_ | 1797582143394676736 |
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| author | Mario Martos Isidro M. Pastor |
| author_facet | Mario Martos Isidro M. Pastor |
| author_sort | Mario Martos |
| collection | DOAJ |
| description | Low transition temperature mixtures (LTTMs) are a new generation of solvents that have found extensive application in organic synthesis. The interactions between the components often generate highly activated, catalytically active species, thus opening the possibility of using LTTMs as catalysts, rather than solvents. In this work, we introduce a nickel-based imidazolium LTTM, study its thermal behavior and explore its catalytic activity in the solvent-free allylation of heterocycles with allylic alcohols. This system is effective in this reaction, affording the corresponding products in excellent yield without the need for additional purifications, thus resulting in a very environmentally friendly protocol. |
| first_indexed | 2024-03-10T23:16:45Z |
| format | Article |
| id | doaj.art-ca1420f34eaa4162a438f3e3d0df82ef |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-10T23:16:45Z |
| publishDate | 2023-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-ca1420f34eaa4162a438f3e3d0df82ef2023-11-19T08:34:48ZengMDPI AGMolecules1420-30492023-08-012817633810.3390/molecules28176338Nickel-Imidazolium Low Transition Temperature Mixtures with Lewis-Acidic CharacterMario Martos0Isidro M. Pastor1Institute of Organic Synthesis, University of Alicante, ctra. San Vicente del Raspeig s/n, San Vicente del Raspeig, 03690 Alicante, SpainInstitute of Organic Synthesis, University of Alicante, ctra. San Vicente del Raspeig s/n, San Vicente del Raspeig, 03690 Alicante, SpainLow transition temperature mixtures (LTTMs) are a new generation of solvents that have found extensive application in organic synthesis. The interactions between the components often generate highly activated, catalytically active species, thus opening the possibility of using LTTMs as catalysts, rather than solvents. In this work, we introduce a nickel-based imidazolium LTTM, study its thermal behavior and explore its catalytic activity in the solvent-free allylation of heterocycles with allylic alcohols. This system is effective in this reaction, affording the corresponding products in excellent yield without the need for additional purifications, thus resulting in a very environmentally friendly protocol.https://www.mdpi.com/1420-3049/28/17/6338low transition temperature mixturesallylic alcoholsimidazolium saltstetrachloronickelatessustainable chemistry |
| spellingShingle | Mario Martos Isidro M. Pastor Nickel-Imidazolium Low Transition Temperature Mixtures with Lewis-Acidic Character Molecules low transition temperature mixtures allylic alcohols imidazolium salts tetrachloronickelates sustainable chemistry |
| title | Nickel-Imidazolium Low Transition Temperature Mixtures with Lewis-Acidic Character |
| title_full | Nickel-Imidazolium Low Transition Temperature Mixtures with Lewis-Acidic Character |
| title_fullStr | Nickel-Imidazolium Low Transition Temperature Mixtures with Lewis-Acidic Character |
| title_full_unstemmed | Nickel-Imidazolium Low Transition Temperature Mixtures with Lewis-Acidic Character |
| title_short | Nickel-Imidazolium Low Transition Temperature Mixtures with Lewis-Acidic Character |
| title_sort | nickel imidazolium low transition temperature mixtures with lewis acidic character |
| topic | low transition temperature mixtures allylic alcohols imidazolium salts tetrachloronickelates sustainable chemistry |
| url | https://www.mdpi.com/1420-3049/28/17/6338 |
| work_keys_str_mv | AT mariomartos nickelimidazoliumlowtransitiontemperaturemixtureswithlewisacidiccharacter AT isidrompastor nickelimidazoliumlowtransitiontemperaturemixtureswithlewisacidiccharacter |