One-month spaceflight compromises the bone microstructure, tissue-level mechanical properties, osteocyte survival and lacunae volume in mature mice skeletons

One-month spaceflight compromises the bone microstructure, tissue-level mechanical properties, osteocyte survival and lacunae volume in mature mice skeletons

Abstract The weightless environment during spaceflight induces site-specific bone loss. The 30-day Bion-M1 mission offered a unique opportunity to characterize the skeletal changes after spaceflight and an 8-day recovery period in mature male C57/BL6 mice. In the femur metaphysis, spaceflight decrea...

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Bibliographic Details
Main Authors: Maude Gerbaix, Vasily Gnyubkin, Delphine Farlay, Cécile Olivier, Patrick Ammann, Guillaume Courbon, Norbert Laroche, Rachel Genthial, Hélène Follet, Françoise Peyrin, Boris Shenkman, Guillemette Gauquelin-Koch, Laurence Vico
Format: Article
Language:English
Published: Nature Portfolio 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-03014-2

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