Glycosylation Alterations in Multiple Sclerosis Show Increased Proinflammatory Potential

Glycosylation Alterations in Multiple Sclerosis Show Increased Proinflammatory Potential

Multiple sclerosis (MS) is an inflammatory autoimmune disorder affecting the central nervous system (CNS), with unresolved aetiology. Previous studies have implicated N-glycosylation, a highly regulated enzymatic attachment of complex sugars to targeted proteins, in MS pathogenesis. We investigated...

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Bibliographic Details
Main Authors: Ana Cvetko, Domagoj Kifer, Olga Gornik, Lucija Klarić, Elizabeth Visser, Gordan Lauc, James F. Wilson, Tamara Štambuk
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Biomedicines
Subjects:
immunoglobulin G in inflammation
multiple sclerosis
N-glycosylation
plasma glycoproteins
biomarkers
Online Access:https://www.mdpi.com/2227-9059/8/10/410

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