Effects of two alveolar recruitment maneuvers in an “open-lung” approach during laparoscopy in dogs
ObjectivesThe aim of this study was to compare the effects of a sustained inflation alveolar recruiting maneuver (ARM) followed by 5 cmH2O of PEEP and a stepwise ARM, in dogs undergoing laparoscopic surgery.Materials and methodsTwenty adult dogs were enrolled in this prospective randomized clinical...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-08-01
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| Series: | Frontiers in Veterinary Science |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fvets.2022.904673/full |
| _version_ | 1818485952602963968 |
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| author | Caterina Di Bella Caterina Vicenti Joaquin Araos Luca Lacitignola Laura Fracassi Marzia Stabile Salvatore Grasso Alberto Crovace Francesco Staffieri |
| author_facet | Caterina Di Bella Caterina Vicenti Joaquin Araos Luca Lacitignola Laura Fracassi Marzia Stabile Salvatore Grasso Alberto Crovace Francesco Staffieri |
| author_sort | Caterina Di Bella |
| collection | DOAJ |
| description | ObjectivesThe aim of this study was to compare the effects of a sustained inflation alveolar recruiting maneuver (ARM) followed by 5 cmH2O of PEEP and a stepwise ARM, in dogs undergoing laparoscopic surgery.Materials and methodsTwenty adult dogs were enrolled in this prospective randomized clinical study. Dogs were premedicated with methadone intramuscularly (IM); anesthesia was induced with propofol intravenously (IV) and maintained with inhaled isoflurane in pure oxygen. The baseline ventilatory setting (BVS) was as follows: tidal volume of 15 mL/kg, inspiratory pause of 25%, inspiratory to expiratory ratio of 1:2, and the respiratory rate to maintain the end-tidal carbon dioxide between 45 and 55 mmHg. 10 min after pneumoperitoneum, randomly, 10 dogs underwent sustained inflation ARM followed by 5 cmH2O of PEEP (ARMi), while 10 dogs underwent a stepwise recruitment maneuver followed by the setting of the “best PEEP” (ARMc). Gas exchange, respiratory system mechanics, and hemodynamic were evaluated before the pneumoperitoneum induction (BASE), 10 min after the pneumoperitoneum (PP), 10 min after the recruitment (ARM), and 10 min after the pneumoperitoneum resolution (PostPP). Statistical analysis was performed with the ANOVA test (p < 0.05).ResultsStatic compliance decreased in both groups at PP (ARMc = 1.35 ± 0.21; ARMi = 1.16 ± 0.26 mL/cmH2O/kg) compared to BASE (ARMc = 1.78 ± 0.60; ARMi = 1.66 ± 0.66 mL/cmH2O/kg) and at ARM (ARMc = 1.71 ± 0.41; ARMi = 1.44 ± 0.84 mL/cmH2O/kg) and PostPP (ARMc = 1.75 ± 0.45; ARMi = 1.89 ± 0.59 mL/cmH2O/kg), and it was higher compared to PP and similar to BASE. The PaO2/FiO2, in both groups, was higher at ARM (ARMc = 455.11 ± 85.90; ARMi = 505.40 ± 31.70) and PostPP (ARMc = 521.30 ± 66.20; ARMi = 450.90 ± 70.60) compared to PP (ARMc = 369.53 ± 49.31; ARMi = 394.32 ± 37.72).Conclusion and clinical relevanceThe two ARMs improve lung function in dogs undergoing laparoscopic surgery similarly. Application of PEEP at the end of the ARMs prolonged the effects of the open-lung strategy. |
| first_indexed | 2024-12-10T16:16:23Z |
| format | Article |
| id | doaj.art-ca1d3d7dd3374b5fb84c091779e054f2 |
| institution | Directory Open Access Journal |
| issn | 2297-1769 |
| language | English |
| last_indexed | 2024-12-10T16:16:23Z |
| publishDate | 2022-08-01 |
| publisher | Frontiers Media S.A. |
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| series | Frontiers in Veterinary Science |
| spelling | doaj.art-ca1d3d7dd3374b5fb84c091779e054f22022-12-22T01:41:58ZengFrontiers Media S.A.Frontiers in Veterinary Science2297-17692022-08-01910.3389/fvets.2022.904673904673Effects of two alveolar recruitment maneuvers in an “open-lung” approach during laparoscopy in dogsCaterina Di Bella0Caterina Vicenti1Joaquin Araos2Luca Lacitignola3Laura Fracassi4Marzia Stabile5Salvatore Grasso6Alberto Crovace7Francesco Staffieri8School of Bioscience and Veterinary Medicine, University of Camerino, Camerino, ItalySection of Veterinary Clinics and Animal Production, Department of Emergency and Organ Transplantations, University of Bari, Bari, ItalyDepartment of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, United StatesSection of Veterinary Clinics and Animal Production, Department of Emergency and Organ Transplantations, University of Bari, Bari, ItalySection of Veterinary Clinics and Animal Production, Department of Emergency and Organ Transplantations, University of Bari, Bari, ItalySection of Veterinary Clinics and Animal Production, Department of Emergency and Organ Transplantations, University of Bari, Bari, ItalySection of Anesthesia and Intensive Care, Department of Emergency and Organ Transplantations, University of Bari, Bari, ItalySection of Veterinary Clinics and Animal Production, Department of Emergency and Organ Transplantations, University of Bari, Bari, ItalySection of Veterinary Clinics and Animal Production, Department of Emergency and Organ Transplantations, University of Bari, Bari, ItalyObjectivesThe aim of this study was to compare the effects of a sustained inflation alveolar recruiting maneuver (ARM) followed by 5 cmH2O of PEEP and a stepwise ARM, in dogs undergoing laparoscopic surgery.Materials and methodsTwenty adult dogs were enrolled in this prospective randomized clinical study. Dogs were premedicated with methadone intramuscularly (IM); anesthesia was induced with propofol intravenously (IV) and maintained with inhaled isoflurane in pure oxygen. The baseline ventilatory setting (BVS) was as follows: tidal volume of 15 mL/kg, inspiratory pause of 25%, inspiratory to expiratory ratio of 1:2, and the respiratory rate to maintain the end-tidal carbon dioxide between 45 and 55 mmHg. 10 min after pneumoperitoneum, randomly, 10 dogs underwent sustained inflation ARM followed by 5 cmH2O of PEEP (ARMi), while 10 dogs underwent a stepwise recruitment maneuver followed by the setting of the “best PEEP” (ARMc). Gas exchange, respiratory system mechanics, and hemodynamic were evaluated before the pneumoperitoneum induction (BASE), 10 min after the pneumoperitoneum (PP), 10 min after the recruitment (ARM), and 10 min after the pneumoperitoneum resolution (PostPP). Statistical analysis was performed with the ANOVA test (p < 0.05).ResultsStatic compliance decreased in both groups at PP (ARMc = 1.35 ± 0.21; ARMi = 1.16 ± 0.26 mL/cmH2O/kg) compared to BASE (ARMc = 1.78 ± 0.60; ARMi = 1.66 ± 0.66 mL/cmH2O/kg) and at ARM (ARMc = 1.71 ± 0.41; ARMi = 1.44 ± 0.84 mL/cmH2O/kg) and PostPP (ARMc = 1.75 ± 0.45; ARMi = 1.89 ± 0.59 mL/cmH2O/kg), and it was higher compared to PP and similar to BASE. The PaO2/FiO2, in both groups, was higher at ARM (ARMc = 455.11 ± 85.90; ARMi = 505.40 ± 31.70) and PostPP (ARMc = 521.30 ± 66.20; ARMi = 450.90 ± 70.60) compared to PP (ARMc = 369.53 ± 49.31; ARMi = 394.32 ± 37.72).Conclusion and clinical relevanceThe two ARMs improve lung function in dogs undergoing laparoscopic surgery similarly. Application of PEEP at the end of the ARMs prolonged the effects of the open-lung strategy.https://www.frontiersin.org/articles/10.3389/fvets.2022.904673/fulllaparoscopyatelectasisalveolar recruitmentoxygenationdog |
| spellingShingle | Caterina Di Bella Caterina Vicenti Joaquin Araos Luca Lacitignola Laura Fracassi Marzia Stabile Salvatore Grasso Alberto Crovace Francesco Staffieri Effects of two alveolar recruitment maneuvers in an “open-lung” approach during laparoscopy in dogs Frontiers in Veterinary Science laparoscopy atelectasis alveolar recruitment oxygenation dog |
| title | Effects of two alveolar recruitment maneuvers in an “open-lung” approach during laparoscopy in dogs |
| title_full | Effects of two alveolar recruitment maneuvers in an “open-lung” approach during laparoscopy in dogs |
| title_fullStr | Effects of two alveolar recruitment maneuvers in an “open-lung” approach during laparoscopy in dogs |
| title_full_unstemmed | Effects of two alveolar recruitment maneuvers in an “open-lung” approach during laparoscopy in dogs |
| title_short | Effects of two alveolar recruitment maneuvers in an “open-lung” approach during laparoscopy in dogs |
| title_sort | effects of two alveolar recruitment maneuvers in an open lung approach during laparoscopy in dogs |
| topic | laparoscopy atelectasis alveolar recruitment oxygenation dog |
| url | https://www.frontiersin.org/articles/10.3389/fvets.2022.904673/full |
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