Opistorchis felineus invasion influence on immunity in bronchial asthma
To investigate the molecular mechanisms of human immune response modification by Opisthorchis felineus antigens in bronchial asthma. The experimental study was performed with cell cultures from patients with bronchial asthma, patients with opisthorchiasis, and patients with BA and opisthorchiasis co...
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Format: | Article |
Language: | English |
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Siberian State Medical University (Tomsk)
2010-06-01
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Series: | Бюллетень сибирской медицины |
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Online Access: | https://bulletin.ssmu.ru/jour/article/view/1601 |
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author | L. M. Ogorodova M. B. Freidin A. E. Sazonov O. S. Fyodorova I. A. Deyev Ye. E. Kremer |
author_facet | L. M. Ogorodova M. B. Freidin A. E. Sazonov O. S. Fyodorova I. A. Deyev Ye. E. Kremer |
author_sort | L. M. Ogorodova |
collection | DOAJ |
description | To investigate the molecular mechanisms of human immune response modification by Opisthorchis felineus antigens in bronchial asthma. The experimental study was performed with cell cultures from patients with bronchial asthma, patients with opisthorchiasis, and patients with BA and opisthorchiasis co-occurred. A proposed down-regulation of immune response by higher level of IL10 and TGFB genes expression in patients with opisthorchiasis was revealed. |
first_indexed | 2024-04-10T01:11:17Z |
format | Article |
id | doaj.art-ca20301075cf4d46b232858a978dbd58 |
institution | Directory Open Access Journal |
issn | 1682-0363 1819-3684 |
language | English |
last_indexed | 2024-04-10T01:11:17Z |
publishDate | 2010-06-01 |
publisher | Siberian State Medical University (Tomsk) |
record_format | Article |
series | Бюллетень сибирской медицины |
spelling | doaj.art-ca20301075cf4d46b232858a978dbd582023-03-13T09:58:13ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842010-06-0193859010.20538/1682-0363-2010-3-85-901104Opistorchis felineus invasion influence on immunity in bronchial asthmaL. M. Ogorodova0M. B. Freidin1A. E. Sazonov2O. S. Fyodorova3I. A. Deyev4Ye. E. Kremer5Сибирский государственный медицинский университетНИИ медицинской генетики СО РАМНСибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетTo investigate the molecular mechanisms of human immune response modification by Opisthorchis felineus antigens in bronchial asthma. The experimental study was performed with cell cultures from patients with bronchial asthma, patients with opisthorchiasis, and patients with BA and opisthorchiasis co-occurred. A proposed down-regulation of immune response by higher level of IL10 and TGFB genes expression in patients with opisthorchiasis was revealed.https://bulletin.ssmu.ru/jour/article/view/1601инвазия opisthorchis felineusбронхиальная астмаиммунный ответэкспрессия генов |
spellingShingle | L. M. Ogorodova M. B. Freidin A. E. Sazonov O. S. Fyodorova I. A. Deyev Ye. E. Kremer Opistorchis felineus invasion influence on immunity in bronchial asthma Бюллетень сибирской медицины инвазия opisthorchis felineus бронхиальная астма иммунный ответ экспрессия генов |
title | Opistorchis felineus invasion influence on immunity in bronchial asthma |
title_full | Opistorchis felineus invasion influence on immunity in bronchial asthma |
title_fullStr | Opistorchis felineus invasion influence on immunity in bronchial asthma |
title_full_unstemmed | Opistorchis felineus invasion influence on immunity in bronchial asthma |
title_short | Opistorchis felineus invasion influence on immunity in bronchial asthma |
title_sort | opistorchis felineus invasion influence on immunity in bronchial asthma |
topic | инвазия opisthorchis felineus бронхиальная астма иммунный ответ экспрессия генов |
url | https://bulletin.ssmu.ru/jour/article/view/1601 |
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