Auxotrophy to Xeno-DNA: an exploration of combinatorial mechanisms for a high-fidelity biosafety system for synthetic biology applications

Auxotrophy to Xeno-DNA: an exploration of combinatorial mechanisms for a high-fidelity biosafety system for synthetic biology applications

Abstract Background Biosafety is a key aspect in the international Genetically Engineered Machine (iGEM) competition, which offers student teams an amazing opportunity to pursue their own research projects in the field of Synthetic Biology. iGEM projects often involve the creation of genetically eng...

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Bibliographic Details
Main Authors: Christopher M. Whitford, Saskia Dymek, Denise Kerkhoff, Camilla März, Olga Schmidt, Maximilian Edich, Julian Droste, Boas Pucker, Christian Rückert, Jörn Kalinowski
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Journal of Biological Engineering
Subjects:
Kill switch
iGEM
Semantic containment
Physical containment
Auxotrophy
Escherichia coli
Online Access:http://link.springer.com/article/10.1186/s13036-018-0105-8

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