Fine‐Tuning of Cholesterol Homeostasis Controls Erythroid Differentiation

Fine‐Tuning of Cholesterol Homeostasis Controls Erythroid Differentiation

Abstract Lipid metabolism is essential for stemness maintenance, self‐renewal, and differentiation of stem cells, however, the regulatory function of cholesterol metabolism in erythroid differentiation is poorly studied. In the present study, a critical role for cholesterol homeostasis in terminal e...

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Bibliographic Details
Main Authors: Zhiyuan Lu, Lixia Huang, Yanxia Li, Yan Xu, Ruihao Zhang, Qian Zhou, Qi Sun, Yi Lu, Junjie Chen, Yuemao Shen, Jian Li, Baobing Zhao
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Advanced Science
Subjects:
cholesterol homeostasis
enucleation
erythropoiesis
GATA1
ribosome biogenesis
SREBP2
Online Access:https://doi.org/10.1002/advs.202102669

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