Protease-Based Subunit Vaccine in Mice Boosts BCG Protection against <i>Mycobacterium tuberculosis</i>

Protease-Based Subunit Vaccine in Mice Boosts BCG Protection against <i>Mycobacterium tuberculosis</i>

The significant number of people with latent and active tuberculosis infection requires further efforts to develop new vaccines or improve the Bacillus Calmette-Guérin (BCG), which is the only approved vaccine against this disease. In this study, we developed a recombinant fusion protein (PEPf) cont...

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Bibliographic Details
Main Authors: Ana Paula Junqueira-Kipnis, Carine de Castro Souza, Ana Carolina de Oliveira Carvalho, Fabio Muniz de Oliveira, Vinnycius Pereira Almeida, Alisson Rodrigues de Paula, Mara Rubia Celes, André Kipnis
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Vaccines
Subjects:
tuberculosis
subunit vaccine
PepN
PepA/Mtb32a
Msh1
recombinant BCG
Online Access:https://www.mdpi.com/2076-393X/10/2/306

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