Human β-Defensin 2 Mutations Are Associated With Asthma and Atopy in Children and Its Application Prevents Atopic Asthma in a Mouse Model

Human β-Defensin 2 Mutations Are Associated With Asthma and Atopy in Children and Its Application Prevents Atopic Asthma in a Mouse Model

Asthma and allergies are complex, chronic inflammatory diseases in which genetic and environmental factors are crucial. Protection against asthma and allergy development in the context of farming environment is established by early animal contact, unpasteurized milk consumption and gut microbiota ma...

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Bibliographic Details
Main Authors: Natascha S. Borchers, Elisangela Santos-Valente, Antoaneta A. Toncheva, Jan Wehkamp, Andre Franke, Vincent D. Gaertner, Peter Nordkild, Jon Genuneit, Benjamin A. H. Jensen, Michael Kabesch
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
hBD-2
asthma
atopy
prevention
defensin
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.636061/full

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