Non-Toxigenic <i>Clostridioides difficile</i> Strain E4 (NTCD-E4) Prevents Establishment of Primary <i>C. difficile</i> Infection by Epidemic PCR Ribotype 027 in an In Vitro Human Gut Model

Non-Toxigenic <i>Clostridioides difficile</i> Strain E4 (NTCD-E4) Prevents Establishment of Primary <i>C. difficile</i> Infection by Epidemic PCR Ribotype 027 in an In Vitro Human Gut Model

<i>Clostridioides difficile</i> infection (CDI) remains a significant healthcare burden. Non-toxigenic <i>C. difficile</i> (NTCD) strains have shown a benefit in preventing porcine enteritis and in human recurrent CDI. In this study, we evaluated the efficacy of metronidazole...

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Bibliographic Details
Main Authors: Perezimor Etifa, César Rodríguez, Céline Harmanus, Ingrid M. J. G. Sanders, Igor A. Sidorov, Olufunmilayo A. Mohammed, Emily Savage, Andrew R. Timms, Jane Freeman, Wiep Klaas Smits, Mark H. Wilcox, Simon D. Baines
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Antibiotics
Subjects:
<i>Clostridioides difficile</i>
RT027
non-toxigenic
antibiotics
resistance
gut model
Online Access:https://www.mdpi.com/2079-6382/12/3/435

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