Development of a Highly Efficient CRISPR/Cas9-Mediated Herpesvirus of Turkey-Based Vaccine against Novel Variant Infectious Bursal Disease Virus

Development of a Highly Efficient CRISPR/Cas9-Mediated Herpesvirus of Turkey-Based Vaccine against Novel Variant Infectious Bursal Disease Virus

Infectious bursal disease (IBD), caused by IBD virus (IBDV), is an extremely contagious immunosuppressive disease that causes major losses for the poultry industry worldwide. Recently, the novel variant IBDV (G2d) has been highly prevalent in Korea, but the current vaccines against this very virulen...

Full description

Bibliographic Details
Main Authors:	Jun-Feng Zhang, Jong-Yeol Park, Sang-Won Kim, Yu-Ri Choi, Se-Yeoun Cha, Hyung-Kwan Jang, Bai Wei, Min Kang
Format:	Article
Language:	English
Published:	MDPI AG 2024-02-01
Series:	Vaccines
Subjects:	variant infectious bursal disease virus recombinant vector vaccine herpesvirus of turkeys CRISPR/Cas9
Online Access:	https://www.mdpi.com/2076-393X/12/3/226

Similar Items

Application of CRISPR/Cas9 for Rapid Genome Editing of Pseudorabies Virus and Bovine Herpesvirus-1
by: Wanqi Yu, et al.
Published: (2024-02-01)

Application of HDR-CRISPR/Cas9 and Erythrocyte Binding for Rapid Generation of Recombinant Turkey Herpesvirus-Vectored Avian Influenza Virus Vaccines
by: Pengxiang Chang, et al.
Published: (2019-11-01)

A Recombinant Turkey Herpesvirus Expressing the F Protein of Newcastle Disease Virus Genotype XII Generated by NHEJ-CRISPR/Cas9 and Cre-LoxP Systems Confers Protection against Genotype XII Challenge in Chickens
by: Katherine Calderón, et al.
Published: (2022-04-01)

Construction of a Novel Infectious Clone of Recombinant Herpesvirus of Turkey Fc-126 Expressing VP2 of IBDV
by: Abid Ullah Shah, et al.
Published: (2022-08-01)

Protection of Chickens against H9N2 Avian Influenza Isolates with a Live Vector Vaccine Expressing Influenza Hemagglutinin Gene Derived from Y280 Avian Influenza Virus
by: Jun-Feng Zhang, et al.
Published: (2024-03-01)

Pathogenicity and immunogenicity of gI/gE/TK-gene-deleted Felid herpesvirus 1 variants in cats
by: Aoxing Tang, et al.
Published: (2023-05-01)

A New Strategy for Efficient Screening and Identification of Monoclonal Antibodies against Oncogenic Avian Herpesvirus Utilizing CRISPR/Cas9-Based Gene-Editing Technology
by: Man Teng, et al.
Published: (2022-09-01)

CRISPR-Cas9 Screening of Kaposi’s Sarcoma-Associated Herpesvirus-Transformed Cells Identifies XPO1 as a Vulnerable Target of Cancer Cells
by: Marion Gruffaz, et al.
Published: (2019-06-01)

Fundamental CRISPR-Cas9 tools and current applications in microbial systems
by: Pingfang Tian, et al.
Published: (2017-09-01)

Characterization and pathogenicity of a novel variant infectious bursal disease virus in China
by: Yuanling Huang, et al.
Published: (2023-03-01)

Anti‐CRISPRs: The natural inhibitors for CRISPR‐Cas systems
by: Fei Zhang, et al.
Published: (2019-06-01)

Antiviral strategies targeting herpesviruses
by: Haisi Dong, et al.
Published: (2021-09-01)

Infectious Bursal Disease: Pathogenicity and Immunogenicity of Vaccines
by: E Camilotti, et al.

Histopathological and immunohistochemical diagnosis of infectious bursal disease in poultry birds
by: J. Singh, et al.
Published: (2015-11-01)

Identification of the EH CRISPR‐Cas9 system on a metagenome and its application to genome engineering
by: Belen Esquerra‐Ruvira, et al.
Published: (2023-07-01)

Crispr/Cas System: An Effective Tool Against Pathogenic Diseases
by: Aslam Shakira, et al.
Published: (2023-06-01)

A Preventive Cytokine Treatment of the Viral Infectious Bursal Disease (IBD) of Chickens
by: Rosana Mattiello, et al.
Published: (2015-04-01)

Ghrelin attenuates infectious bursal disease virus–induced early inflammatory response and bursal injury in chicken
by: Yan Yu, et al.
Published: (2020-11-01)

Bioinformational analysis of Yersinia pseudotuberculosis IP32953 CRISPR/cas system
by: N. P. Peretolchina, et al.
Published: (2016-09-01)

INFECTIOUS BURSAL DISEASE (GUMBORO DISEASE)
by: Maja Velhner
Published: (2008-06-01)

Point-of-Care Testing for Infectious Diseases Based on Class 2 CRISPR/Cas Technology
by: Shiu-Jau Chen, et al.
Published: (2023-07-01)

Infectious bursal disease virus: identification of the novel genetic group and reassortant viruses
by: L. O. Scherbakova, et al.
Published: (2022-03-01)

Efficient Cross-Screening and Characterization of Monoclonal Antibodies against Marek’s Disease Specific Meq Oncoprotein Using CRISPR/Cas9-Gene-Edited Viruses
by: Man Teng, et al.
Published: (2023-03-01)

CRISPR-Cas12/Cas13: Bibliometric analysis and systematic review of its application in infectious disease detection
by: Samson Leta, et al.
Published: (2024-05-01)

Molecular and in vivo Characterization of an Iranian Infectious Bursal Disease Virus Containing a Mixed Virus Population
by: Amir Ghorbani, et al.
Published: (1999-11-01)

Potential Application of the CRISPR/Cas9 System against Herpesvirus Infections
by: Yuan-Chuan Chen, et al.
Published: (2018-05-01)

Infectious bursal disease virus in chickens: prevalence, impact, and management strategies
by: Dey S, et al.
Published: (2019-08-01)

Efficient Method for Generating Point Mutations in the Vaccinia Virus Genome Using CRISPR/Cas9
by: Laetitia Boutin, et al.
Published: (2022-07-01)

CRISPR-Cas9 Direct Fusions for Improved Genome Editing via Enhanced Homologous Recombination
by: Tahmina Tabassum, et al.
Published: (2023-09-01)

Efficacy of a Turkey Herpesvirus Vectored Newcastle Disease Vaccine against Genotype VII.1.1 Virus: Challenge Route Affects Shedding Pattern
by: Vilmos Palya, et al.
Published: (2021-01-01)

CRISPR/Cas patents and health-related publications in South America
by: LARIANE FRÂNCIO, et al.
Published: (2023-06-01)

Self-Repairing Herpesvirus Saimiri Deletion Variants
by: Ines Heyn, et al.
Published: (2022-07-01)

THE EFFECT OF DIETARY VITAMIN -C- ON THE SEVERITY OF EXPERIMENETAL INFECTIOUS BURSAL DISEASE IN BROILERS
by: R. N. AL- Taweel
Published: (1994-12-01)

Research Note: “Hidden” infectious bursal disease virus infections in Central Europe
by: Tamás Mató, et al.
Published: (2022-08-01)

MOLECULAR DETECTION OF INFECTIOUS BURSAL DISEASE VIRUS FROM POULTRY IN THRISSUR DISTRICT
by: Thanksy S. Akkara, et al.
Published: (2018-01-01)

INCIDENCE OF INFECTIOUS BURSAL DISEASE AMONG BIRDS SUBMITTED TO A DIAGNOSTIC LABORATORY IN NWFP, PAKISTAN
by: M. Farooq, F.R. Durrani, S. Faisal, A. Asghar1 and A. Khurshid
Published: (2000-04-01)

An analysis of the Asgardarchaea Cas1_3 protein: Experimental characterization of a potential intermediate in the evolution of CRISPR-Cas systems
by: Abramova Marina, et al.
Published: (2024-03-01)

CRISPR-Cas13 in malaria parasite: Diagnosis and prospective gene function identification
by: Elvis Quansah, et al.
Published: (2023-01-01)

The circulation of unique reassortment strains of infectious bursal disease virus in Pakistan
by: Altaf HUSSAIN, et al.
Published: (2020-07-01)

Effect of Force 6® Poultry on Infectious Bursal disease Virus in Vitro
by: Amjed H. . Ulaiwi
Published: (2015-12-01)