Deglycosylation Differentially Regulates Weaned Porcine Gut Alkaline Phosphatase Isoform Functionality along the Longitudinal Axis

Deglycosylation Differentially Regulates Weaned Porcine Gut Alkaline Phosphatase Isoform Functionality along the Longitudinal Axis

Gut alkaline phosphatases (AP) dephosphorylate the lipid moiety of endotoxin and other pathogen-associated-molecular patterns members, thus maintaining gut eubiosis and preventing metabolic endotoxemia. Early weaned pigs experience gut dysbiosis, enteric diseases and growth retardation in associatio...

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Bibliographic Details
Main Authors: Xindi Yin, Weijun Wang, Stephen Y. K. Seah, Yoshinori Mine, Ming Z. Fan
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Pathogens
Subjects:
alkaline phosphatases (AP)
deglycosylation and glycosylation
endotoxemia
gut eubiosis and dysbiosis
homeostasis
weaned pig
Online Access:https://www.mdpi.com/2076-0817/12/3/407

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