Kawain Inhibits Urinary Bladder Carcinogenesis through Epigenetic Inhibition of LSD1 and Upregulation of H3K4 Methylation

Kawain Inhibits Urinary Bladder Carcinogenesis through Epigenetic Inhibition of LSD1 and Upregulation of H3K4 Methylation

Epidemiological evidence suggests that kava (<i>Piper methysticum Forst</i>) drinks may reduce the risk of cancer in South Pacific Island smokers. However, little is known about the anti-carcinogenic effects of kava on tobacco smoking-related bladder cancer and its underlying mechanisms....

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Bibliographic Details
Main Authors: Xia Xu, Xuejiao Tian, Liankun Song, Jun Xie, Joseph C. Liao, Joshua J. Meeks, Xue-Ru Wu, Greg E. Gin, Beverly Wang, Edward Uchio, Xiaolin Zi
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Biomolecules
Subjects:
kava
LSD1
chemoprevention
bladder cancer
Online Access:https://www.mdpi.com/2218-273X/13/3/521

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