Zinc-Substituted Pheophorbide A Is a Safe and Efficient Antivascular Photodynamic Agent

Zinc-Substituted Pheophorbide A Is a Safe and Efficient Antivascular Photodynamic Agent

The present study focuses on the photodynamic activity of zinc-substituted pheophorbide a against human endothelial cells. Previously, zinc pheophorbide a has been shown to be a very potent photosensitizer but also a strong albumin binder. Binding to albumin significantly reduces its availability to...

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Bibliographic Details
Main Authors:	Milena J. Szafraniec, Monika Toporkiewicz, Andrzej Gamian
Format:	Article
Language:	English
Published:	MDPI AG 2022-02-01
Series:	Pharmaceuticals
Subjects:	zinc pheophorbide a chlorophyll derivatives photodynamic therapy serum albumin apoptosis endothelium
Online Access:	https://www.mdpi.com/1424-8247/15/2/235

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