CD147 mediates epidermal malignant transformation through the RSK2/AP-1 pathway

CD147 mediates epidermal malignant transformation through the RSK2/AP-1 pathway

Abstract Background Malignant transformation of the epidermis is an essential process in the pathogenesis of cutaneous squamous-cell carcinoma (cSCC). Although evidence has demonstrated that CD147 plays key roles in various tumors, the role of CD147 in epidermal malignant transformation in vivo rema...

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Bibliographic Details
Main Authors:	Xu Zhang, Yeye Guo, Ta Xiao, Jie Li, Aiyuan Guo, Li Lei, Chong Jin, Qi Long, Juan Su, Mingzhu Yin, Hong Liu, Chao Chen, Zhe Zhou, Susi Zhu, Juan Tao, Shuo Hu, Xiang Chen, Cong Peng
Format:	Article
Language:	English
Published:	BMC 2022-08-01
Series:	Journal of Experimental & Clinical Cancer Research
Subjects:	CD147, Keratinocyte, Malignant transformation, RSK2
Online Access:	https://doi.org/10.1186/s13046-022-02427-w

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