A Review of effectual factors in the Pathogenesis of Leishmania Parasites

Leishmania parasites as the causative agent of leishmaniasis belong to Trypanosomatidae family. Parasite, vector, vertebrate host and environment are major factors in pathogenesis of Leishmania.  Parasite dependent factors are virulence factors which exist in Leishmania species such as LPG, GP63. In...

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Main Authors: Mahmoud Mahami-Oskouei, Mehdi Mohebali, Adel Spotin, Zahra Alizadeh
Format: Article
Language:fas
Published: Ardabil University of Medical Sciences 2018-10-01
Series:Journal of Ardabil University of Medical Sciences
Subjects:
Online Access:http://jarums.arums.ac.ir/browse.php?a_code=A-10-1222-1&slc_lang=en&sid=1
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author Mahmoud Mahami-Oskouei
Mehdi Mohebali
Adel Spotin
Zahra Alizadeh
author_facet Mahmoud Mahami-Oskouei
Mehdi Mohebali
Adel Spotin
Zahra Alizadeh
author_sort Mahmoud Mahami-Oskouei
collection DOAJ
description Leishmania parasites as the causative agent of leishmaniasis belong to Trypanosomatidae family. Parasite, vector, vertebrate host and environment are major factors in pathogenesis of Leishmania.  Parasite dependent factors are virulence factors which exist in Leishmania species such as LPG, GP63. In recent years, the importance of these factors in the field of vaccine and drug has been considered by researchers. Sand fly biting behavior and salivary gland proteins are vector dependent factors which are effective in the Leishmania pathogenesis. Age, gender, nutrition, immune system, infectious diseases, genetic, occupation, socio-economic characteristics, and habitat are vertebrate host mediated factors. Temperature, rainfall, wind and its speed, soil, and continuous changes in climate are also environmental factors. Therefore the aim of this study was to evaluate the pathogenesis of Leishmania parasites.
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spelling doaj.art-ca401abfe29e4e878b996aa0925159ee2022-12-22T00:49:21ZfasArdabil University of Medical SciencesJournal of Ardabil University of Medical Sciences2228-72802228-72992018-10-01183279297A Review of effectual factors in the Pathogenesis of Leishmania ParasitesMahmoud Mahami-Oskouei0Mehdi Mohebali1Adel Spotin2Zahra Alizadeh3 Department of Parasitology and Mycology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran Department of Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Department of Parasitology and Mycology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran Department of Parasitology and Mycology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran Leishmania parasites as the causative agent of leishmaniasis belong to Trypanosomatidae family. Parasite, vector, vertebrate host and environment are major factors in pathogenesis of Leishmania.  Parasite dependent factors are virulence factors which exist in Leishmania species such as LPG, GP63. In recent years, the importance of these factors in the field of vaccine and drug has been considered by researchers. Sand fly biting behavior and salivary gland proteins are vector dependent factors which are effective in the Leishmania pathogenesis. Age, gender, nutrition, immune system, infectious diseases, genetic, occupation, socio-economic characteristics, and habitat are vertebrate host mediated factors. Temperature, rainfall, wind and its speed, soil, and continuous changes in climate are also environmental factors. Therefore the aim of this study was to evaluate the pathogenesis of Leishmania parasites.http://jarums.arums.ac.ir/browse.php?a_code=A-10-1222-1&slc_lang=en&sid=1LeishmaniaPathogenesisSand Fly
spellingShingle Mahmoud Mahami-Oskouei
Mehdi Mohebali
Adel Spotin
Zahra Alizadeh
A Review of effectual factors in the Pathogenesis of Leishmania Parasites
Journal of Ardabil University of Medical Sciences
Leishmania
Pathogenesis
Sand Fly
title A Review of effectual factors in the Pathogenesis of Leishmania Parasites
title_full A Review of effectual factors in the Pathogenesis of Leishmania Parasites
title_fullStr A Review of effectual factors in the Pathogenesis of Leishmania Parasites
title_full_unstemmed A Review of effectual factors in the Pathogenesis of Leishmania Parasites
title_short A Review of effectual factors in the Pathogenesis of Leishmania Parasites
title_sort review of effectual factors in the pathogenesis of leishmania parasites
topic Leishmania
Pathogenesis
Sand Fly
url http://jarums.arums.ac.ir/browse.php?a_code=A-10-1222-1&slc_lang=en&sid=1
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