Hydroxytyrosol Enrichment of Olive Leaf Extracts via Membrane Separation Processes

Antioxidants isolated from plant materials, such as phenolics, have attracted a lot of attention because of their potential uses. This contributes to the idea of the biorefinery, which is a way to produce useful products from biomass waste. <i>Olea europaea</i> byproducts have been exten...

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Main Authors: Costas S. Papageorgiou, Stathis Lymberopoulos, Panagiotis Bakas, Dimitris P. Zagklis, Varvara Sygouni, Christakis A. Paraskeva
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Membranes
Subjects:
Online Access:https://www.mdpi.com/2077-0375/12/11/1027
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author Costas S. Papageorgiou
Stathis Lymberopoulos
Panagiotis Bakas
Dimitris P. Zagklis
Varvara Sygouni
Christakis A. Paraskeva
author_facet Costas S. Papageorgiou
Stathis Lymberopoulos
Panagiotis Bakas
Dimitris P. Zagklis
Varvara Sygouni
Christakis A. Paraskeva
author_sort Costas S. Papageorgiou
collection DOAJ
description Antioxidants isolated from plant materials, such as phenolics, have attracted a lot of attention because of their potential uses. This contributes to the idea of the biorefinery, which is a way to produce useful products from biomass waste. <i>Olea europaea</i> byproducts have been extensively investigated for their large contents in phenolics. Oleuropein is a phenolic compound abundant in olive leaves, with its molecule containing hydroxytyrosol, elenolic acid, and glucose. In this work, olive leaf extracts were treated using different combinations of ultrafiltration and nanofiltration membranes to assess their capacity of facilitating the production of hydroxytyrosol-enriched solutions, either by separating the initially extracted oleuropein or by separating the hydroxytyrosol produced after a hydrolysis step. The best performance was observed when an ultrafiltration membrane (UP010, 10,000 Da) was followed by a nanofiltration membrane (TS40, 200–300 Da) for the treatment of the hydrolyzed extract, increasing the purity of the final product from 25% <i>w/w</i> of the total extracted compounds being hydroxytyrosol when membrane processes were not used to 68% <i>w</i>/<i>w</i>.
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spelling doaj.art-ca401f7f041a4b9e85e90ba69b55f09c2023-11-24T05:47:56ZengMDPI AGMembranes2077-03752022-10-011211102710.3390/membranes12111027Hydroxytyrosol Enrichment of Olive Leaf Extracts via Membrane Separation ProcessesCostas S. Papageorgiou0Stathis Lymberopoulos1Panagiotis Bakas2Dimitris P. Zagklis3Varvara Sygouni4Christakis A. Paraskeva5Laboratory of Transport Phenomena and Physicochemical Hydrodynamics (LTPPH), Department of Chemical Engineering, University of Patras, GR26504 Patras, GreeceLaboratory of Transport Phenomena and Physicochemical Hydrodynamics (LTPPH), Department of Chemical Engineering, University of Patras, GR26504 Patras, GreeceLaboratory of Transport Phenomena and Physicochemical Hydrodynamics (LTPPH), Department of Chemical Engineering, University of Patras, GR26504 Patras, GreeceLaboratory of Transport Phenomena and Physicochemical Hydrodynamics (LTPPH), Department of Chemical Engineering, University of Patras, GR26504 Patras, GreeceLaboratory of Transport Phenomena and Physicochemical Hydrodynamics (LTPPH), Department of Chemical Engineering, University of Patras, GR26504 Patras, GreeceLaboratory of Transport Phenomena and Physicochemical Hydrodynamics (LTPPH), Department of Chemical Engineering, University of Patras, GR26504 Patras, GreeceAntioxidants isolated from plant materials, such as phenolics, have attracted a lot of attention because of their potential uses. This contributes to the idea of the biorefinery, which is a way to produce useful products from biomass waste. <i>Olea europaea</i> byproducts have been extensively investigated for their large contents in phenolics. Oleuropein is a phenolic compound abundant in olive leaves, with its molecule containing hydroxytyrosol, elenolic acid, and glucose. In this work, olive leaf extracts were treated using different combinations of ultrafiltration and nanofiltration membranes to assess their capacity of facilitating the production of hydroxytyrosol-enriched solutions, either by separating the initially extracted oleuropein or by separating the hydroxytyrosol produced after a hydrolysis step. The best performance was observed when an ultrafiltration membrane (UP010, 10,000 Da) was followed by a nanofiltration membrane (TS40, 200–300 Da) for the treatment of the hydrolyzed extract, increasing the purity of the final product from 25% <i>w/w</i> of the total extracted compounds being hydroxytyrosol when membrane processes were not used to 68% <i>w</i>/<i>w</i>.https://www.mdpi.com/2077-0375/12/11/1027olive leaveshydroxytyrosololeuropeinmembrane filtrationultrafiltrationnanofiltration
spellingShingle Costas S. Papageorgiou
Stathis Lymberopoulos
Panagiotis Bakas
Dimitris P. Zagklis
Varvara Sygouni
Christakis A. Paraskeva
Hydroxytyrosol Enrichment of Olive Leaf Extracts via Membrane Separation Processes
Membranes
olive leaves
hydroxytyrosol
oleuropein
membrane filtration
ultrafiltration
nanofiltration
title Hydroxytyrosol Enrichment of Olive Leaf Extracts via Membrane Separation Processes
title_full Hydroxytyrosol Enrichment of Olive Leaf Extracts via Membrane Separation Processes
title_fullStr Hydroxytyrosol Enrichment of Olive Leaf Extracts via Membrane Separation Processes
title_full_unstemmed Hydroxytyrosol Enrichment of Olive Leaf Extracts via Membrane Separation Processes
title_short Hydroxytyrosol Enrichment of Olive Leaf Extracts via Membrane Separation Processes
title_sort hydroxytyrosol enrichment of olive leaf extracts via membrane separation processes
topic olive leaves
hydroxytyrosol
oleuropein
membrane filtration
ultrafiltration
nanofiltration
url https://www.mdpi.com/2077-0375/12/11/1027
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AT stathislymberopoulos hydroxytyrosolenrichmentofoliveleafextractsviamembraneseparationprocesses
AT panagiotisbakas hydroxytyrosolenrichmentofoliveleafextractsviamembraneseparationprocesses
AT dimitrispzagklis hydroxytyrosolenrichmentofoliveleafextractsviamembraneseparationprocesses
AT varvarasygouni hydroxytyrosolenrichmentofoliveleafextractsviamembraneseparationprocesses
AT christakisaparaskeva hydroxytyrosolenrichmentofoliveleafextractsviamembraneseparationprocesses