Association between Troponin I and In-Hospital Mortality of Covid-19 Patients
Background and purpose: A wide range of studies have reported the role of troponin I as a predictor of mortality in infectious diseases. According to the various effect measures in different countries, the aim of present study to determine the relationship between serum troponin I level and mortalit...
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| Format: | Article |
| Language: | English |
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Mazandaran University of Medical Sciences
2023-12-01
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| Series: | Journal of Mazandaran University of Medical Sciences |
| Subjects: | |
| Online Access: | http://jmums.mazums.ac.ir/article-1-19669-en.pdf |
| _version_ | 1797397373997023232 |
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| author | Mahbube Sheikh Nadia Poudine Hossein Pourmasoomi Mahdi Afshari |
| author_facet | Mahbube Sheikh Nadia Poudine Hossein Pourmasoomi Mahdi Afshari |
| author_sort | Mahbube Sheikh |
| collection | DOAJ |
| description | Background and purpose: A wide range of studies have reported the role of troponin I as a predictor of mortality in infectious diseases. According to the various effect measures in different countries, the aim of present study to determine the relationship between serum troponin I level and mortality in hospitalized patients with COVID-19 infection in the east of Iran.
Materials and methods: A case-control study was performed. Cases were 61 Covid-19 hospitalized patients (deceased) and 61 recovered patients (controls) who were matched with the corresponding case for age, sex, and admission date were examined. The association between Troponin I and hospital mortality among those patients was investigated using conditional logistic regression models.
Results: The results of the study revealed that the risk of death in patients with high troponin levels at the beginning of hospitalization was 38% greater than that in individuals with normal troponin levels. However, this relationship was not statistically significant (Odds ratio=1.38, 95% confidence interval: 0.38, 5/0).
Conclusion: The results of our study did not show any findings in favor of the predictive effect of troponin I on the mortality of patients with covid-19 infection. To obtain more accurate results, it is recommended to conduct further longitudinal studies with larger sample sizes and better control of confounding variables. |
| first_indexed | 2024-03-09T01:08:57Z |
| format | Article |
| id | doaj.art-ca432c08dd1b4f9a9a69f3148e830f52 |
| institution | Directory Open Access Journal |
| issn | 1735-9260 1735-9279 |
| language | English |
| last_indexed | 2024-03-09T01:08:57Z |
| publishDate | 2023-12-01 |
| publisher | Mazandaran University of Medical Sciences |
| record_format | Article |
| series | Journal of Mazandaran University of Medical Sciences |
| spelling | doaj.art-ca432c08dd1b4f9a9a69f3148e830f522023-12-11T09:06:01ZengMazandaran University of Medical SciencesJournal of Mazandaran University of Medical Sciences1735-92601735-92792023-12-01332343347Association between Troponin I and In-Hospital Mortality of Covid-19 PatientsMahbube Sheikh0Nadia Poudine1Hossein Pourmasoomi2Mahdi Afshari3 Assistant Professor, Department of Cardiology, School of Medicine, Zabol University of Medical Sciences, Zabol, Iran Medical Student, Student Research Committe, School of Medicine, Zabol University of Medical Sciences, Zabol, Iran Assistant Professor, Department of Infectious Diseases, Zabol University of Medical Sciences, Zabol, Iran Professor, Department of Community Medicine, School of Medicine, Zabol University of Medical Sciences, Zabol, Iran Background and purpose: A wide range of studies have reported the role of troponin I as a predictor of mortality in infectious diseases. According to the various effect measures in different countries, the aim of present study to determine the relationship between serum troponin I level and mortality in hospitalized patients with COVID-19 infection in the east of Iran. Materials and methods: A case-control study was performed. Cases were 61 Covid-19 hospitalized patients (deceased) and 61 recovered patients (controls) who were matched with the corresponding case for age, sex, and admission date were examined. The association between Troponin I and hospital mortality among those patients was investigated using conditional logistic regression models. Results: The results of the study revealed that the risk of death in patients with high troponin levels at the beginning of hospitalization was 38% greater than that in individuals with normal troponin levels. However, this relationship was not statistically significant (Odds ratio=1.38, 95% confidence interval: 0.38, 5/0). Conclusion: The results of our study did not show any findings in favor of the predictive effect of troponin I on the mortality of patients with covid-19 infection. To obtain more accurate results, it is recommended to conduct further longitudinal studies with larger sample sizes and better control of confounding variables.http://jmums.mazums.ac.ir/article-1-19669-en.pdftroponin icovid-19mortality |
| spellingShingle | Mahbube Sheikh Nadia Poudine Hossein Pourmasoomi Mahdi Afshari Association between Troponin I and In-Hospital Mortality of Covid-19 Patients Journal of Mazandaran University of Medical Sciences troponin i covid-19 mortality |
| title | Association between Troponin I and In-Hospital Mortality of Covid-19 Patients |
| title_full | Association between Troponin I and In-Hospital Mortality of Covid-19 Patients |
| title_fullStr | Association between Troponin I and In-Hospital Mortality of Covid-19 Patients |
| title_full_unstemmed | Association between Troponin I and In-Hospital Mortality of Covid-19 Patients |
| title_short | Association between Troponin I and In-Hospital Mortality of Covid-19 Patients |
| title_sort | association between troponin i and in hospital mortality of covid 19 patients |
| topic | troponin i covid-19 mortality |
| url | http://jmums.mazums.ac.ir/article-1-19669-en.pdf |
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