Succinate at the Crossroad of Metabolism and Angiogenesis: Roles of SDH, HIF1α and SUCNR1

Succinate at the Crossroad of Metabolism and Angiogenesis: Roles of SDH, HIF1α and SUCNR1

Angiogenesis is an essential process by which new blood vessels develop from existing ones. While adequate angiogenesis is a physiological process during, for example, tissue repair, insufficient and excessive angiogenesis stands on the pathological side. Fine balance between pro- and anti-angiogeni...

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Bibliographic Details
Main Authors: Reham Atallah, Andrea Olschewski, Akos Heinemann
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Biomedicines
Subjects:
succinate
succinate dehydrogenase (SDH)
succinate receptor-1 (SUCNR1)
hypoxia-inducible factor 1-alpha (HIF1α)
angiogenesis
Online Access:https://www.mdpi.com/2227-9059/10/12/3089

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