Efficacy, Safety, and Clinical Outcomes of Splenorenal Shunt Surgery as a Therapeutic Intervention for Portal Hypertension Patients

Highlights: 1. This study systematically reviewed the efficacy, clinical outcomes, and safety of the splenorenal shunt procedure with a comprehensive and meticulous approach. 2. The splenorenal shunt procedure is an innovative surgical intervention that offers a viable option for the management of...

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Main Authors: Yan Efrata Sembiring, Heroe Soebroto, Ito Puruhito, Dhihintia Jiwangga Suta Winarno, I Gusti Agung Made Adnyanya Putra2, Sri Pramesthi Wisnu Bowo Negoro, Ketut Putu Yasa, Jeffrey Jeswant Dillon
Format: Article
Language:English
Published: Universitas Airlangga 2023-09-01
Series:Folia Medica Indonesiana
Subjects:
Online Access:https://e-journal.unair.ac.id/FMI/article/view/48843
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author Yan Efrata Sembiring
Heroe Soebroto
Ito Puruhito
Dhihintia Jiwangga Suta Winarno
I Gusti Agung Made Adnyanya Putra2
Sri Pramesthi Wisnu Bowo Negoro
Ketut Putu Yasa
Jeffrey Jeswant Dillon
author_facet Yan Efrata Sembiring
Heroe Soebroto
Ito Puruhito
Dhihintia Jiwangga Suta Winarno
I Gusti Agung Made Adnyanya Putra2
Sri Pramesthi Wisnu Bowo Negoro
Ketut Putu Yasa
Jeffrey Jeswant Dillon
author_sort Yan Efrata Sembiring
collection DOAJ
description Highlights: 1. This study systematically reviewed the efficacy, clinical outcomes, and safety of the splenorenal shunt procedure with a comprehensive and meticulous approach. 2. The splenorenal shunt procedure is an innovative surgical intervention that offers a viable option for the management of portal hypertension.   Abstract Portal hypertension is the second most common gastrointestinal bleeding in cirrhosis and non-cirrhosis patients. The splenorenal shunt surgery is a potential intervention that may be considered for portal hypertension patients with clinical symptoms such as upper gastrointestinal bleeding caused by the rupture of gastro-esophageal varices. In this study, the researchers aimed to analyze the efficacy, clinical outcomes, and safety of splenorenal shunt surgery in portal hypertension patients. The sources were obtained from electronic search databases, including PubMed, Google Scholar, and ScienceDirect, using the keywords "Efficacy," "Safety," and "Clinical Outcomes." in relation to splenorenal shunt surgery in portal hypertension patients. The researchers set specific criteria for inclusion and exclusion to select the articles. This systematic review revealed the efficacy of the splenorenal shunt procedure with favorable outcomes. The success rate of splenorenal shunt surgery in reducing the clinical symptoms of portal hypertension varied between 66% and 100%. The prevailing complications observed in this study were shunt thrombosis, rebleeding, and thrombocytopenia. However, notable improvements could be achieved with general treatment. In terms of short- and long-term clinical outcomes, the splenorenal shunt procedure demonstrated favorable results. It can be concluded that splenorenal shunt surgery provides excellent clinical outcomes and should be considered a viable treatment option for patients with both cirrhotic and non-cirrhotic portal hypertension.
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spelling doaj.art-ca4a57dbea924f4c8486d82a2b133a132024-03-21T05:20:11ZengUniversitas AirlanggaFolia Medica Indonesiana2355-83932599-056X2023-09-0159330231210.20473/fmi.v59i3.4884346952Efficacy, Safety, and Clinical Outcomes of Splenorenal Shunt Surgery as a Therapeutic Intervention for Portal Hypertension PatientsYan Efrata Sembiring0https://orcid.org/0000-0002-1712-1816Heroe Soebroto1https://orcid.org/0000-0001-7422-2624Ito Puruhito2https://orcid.org/0000-0003-2292-5402Dhihintia Jiwangga Suta Winarno3https://orcid.org/0000-0002-6767-0768I Gusti Agung Made Adnyanya Putra24https://orcid.org/0000-0001-6778-0038Sri Pramesthi Wisnu Bowo Negoro5https://orcid.org/0009-0004-8436-414XKetut Putu Yasa6https://orcid.org/0000-0003-3186-0073Jeffrey Jeswant Dillon7https://orcid.org/0009-0008-0244-9078Department of Thoracic, Cardiac, and Vascular Surgery, Faculty of Medicine, Universitas Airlangga; Dr. Soetomo General Academic Hospital, Surabaya, IndonesiaDepartment of Thoracic, Cardiac, and Vascular Surgery, Faculty of Medicine, Universitas Airlangga; Dr. Soetomo General Academic Hospital, Surabaya, IndonesiaDepartment of Thoracic, Cardiac, and Vascular Surgery, Faculty of Medicine, Universitas Airlangga; Dr. Soetomo General Academic Hospital, Surabaya, IndonesiaDepartment of Thoracic, Cardiac, and Vascular Surgery, Faculty of Medicine, Universitas Airlangga; Dr. Soetomo General Academic Hospital, Surabaya, IndonesiaThoracic, Cardiac, and Vascular Surgery Residency Program, Faculty of Medicine, Universitas Airlangga, Surabaya, IndonesiaThoracic, Cardiac, and Vascular Surgery Residency Program, Faculty of Medicine, Universitas Airlangga, Surabaya, IndonesiaDepartment of Thoracic, Cardiac, and Vascular Surgery, Faculty of Medicine, Universitas Udayana; Prof. Dr. IGNG Ngoerah Central General Hospital, Denpasar, IndonesiaDepartment of Cardiothoracic Surgery, Institut Jantung Negara, Kuala Lumpur, Malaysia Highlights: 1. This study systematically reviewed the efficacy, clinical outcomes, and safety of the splenorenal shunt procedure with a comprehensive and meticulous approach. 2. The splenorenal shunt procedure is an innovative surgical intervention that offers a viable option for the management of portal hypertension.   Abstract Portal hypertension is the second most common gastrointestinal bleeding in cirrhosis and non-cirrhosis patients. The splenorenal shunt surgery is a potential intervention that may be considered for portal hypertension patients with clinical symptoms such as upper gastrointestinal bleeding caused by the rupture of gastro-esophageal varices. In this study, the researchers aimed to analyze the efficacy, clinical outcomes, and safety of splenorenal shunt surgery in portal hypertension patients. The sources were obtained from electronic search databases, including PubMed, Google Scholar, and ScienceDirect, using the keywords "Efficacy," "Safety," and "Clinical Outcomes." in relation to splenorenal shunt surgery in portal hypertension patients. The researchers set specific criteria for inclusion and exclusion to select the articles. This systematic review revealed the efficacy of the splenorenal shunt procedure with favorable outcomes. The success rate of splenorenal shunt surgery in reducing the clinical symptoms of portal hypertension varied between 66% and 100%. The prevailing complications observed in this study were shunt thrombosis, rebleeding, and thrombocytopenia. However, notable improvements could be achieved with general treatment. In terms of short- and long-term clinical outcomes, the splenorenal shunt procedure demonstrated favorable results. It can be concluded that splenorenal shunt surgery provides excellent clinical outcomes and should be considered a viable treatment option for patients with both cirrhotic and non-cirrhotic portal hypertension.https://e-journal.unair.ac.id/FMI/article/view/48843portal hypertensionsplenorenal shuntefficacyclinical outcomeshuman and health
spellingShingle Yan Efrata Sembiring
Heroe Soebroto
Ito Puruhito
Dhihintia Jiwangga Suta Winarno
I Gusti Agung Made Adnyanya Putra2
Sri Pramesthi Wisnu Bowo Negoro
Ketut Putu Yasa
Jeffrey Jeswant Dillon
Efficacy, Safety, and Clinical Outcomes of Splenorenal Shunt Surgery as a Therapeutic Intervention for Portal Hypertension Patients
Folia Medica Indonesiana
portal hypertension
splenorenal shunt
efficacy
clinical outcomes
human and health
title Efficacy, Safety, and Clinical Outcomes of Splenorenal Shunt Surgery as a Therapeutic Intervention for Portal Hypertension Patients
title_full Efficacy, Safety, and Clinical Outcomes of Splenorenal Shunt Surgery as a Therapeutic Intervention for Portal Hypertension Patients
title_fullStr Efficacy, Safety, and Clinical Outcomes of Splenorenal Shunt Surgery as a Therapeutic Intervention for Portal Hypertension Patients
title_full_unstemmed Efficacy, Safety, and Clinical Outcomes of Splenorenal Shunt Surgery as a Therapeutic Intervention for Portal Hypertension Patients
title_short Efficacy, Safety, and Clinical Outcomes of Splenorenal Shunt Surgery as a Therapeutic Intervention for Portal Hypertension Patients
title_sort efficacy safety and clinical outcomes of splenorenal shunt surgery as a therapeutic intervention for portal hypertension patients
topic portal hypertension
splenorenal shunt
efficacy
clinical outcomes
human and health
url https://e-journal.unair.ac.id/FMI/article/view/48843
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