Three-Dimensional Analysis of the Nasolacrimal Duct and Nasal Cavity and Arrangement of Mucosal Tissue in Chickens
The nasal mucosa plays an important role in the immune system, with nasal mucous cells secreting mucin that, along with pili, exclude foreign substances from intervening. Nasal mucosal-associated lymphoid tissue (NALT), present in the nasal lamina propria, acts as a local immune system. In birds, th...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Japan Poultry Science Association
2020-10-01
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| Series: | The Journal of Poultry Science |
| Subjects: | |
| Online Access: | https://www.jstage.jst.go.jp/article/jpsa/57/4/57_0190091/_html/-char/en |
| _version_ | 1827939035487666176 |
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| author | Takafumi Watanabe Naoki Takahashi Jun Minaguchi Ayaka Mochizuki Kohzy Hiramatsu |
| author_facet | Takafumi Watanabe Naoki Takahashi Jun Minaguchi Ayaka Mochizuki Kohzy Hiramatsu |
| author_sort | Takafumi Watanabe |
| collection | DOAJ |
| description | The nasal mucosa plays an important role in the immune system, with nasal mucous cells secreting mucin that, along with pili, exclude foreign substances from intervening. Nasal mucosal-associated lymphoid tissue (NALT), present in the nasal lamina propria, acts as a local immune system. In birds, the Harderian gland in the orbit also plays an important role in the local immune system. In this study, we analyzed the pathway from the nasolacrimal duct to the nasal cavity in chickens and the distribution of the nasal mucous cells responsible for defense mechanisms against pathogens. To determine the three-dimensional structure of the pathway from the nasolacrimal duct to the nasal cavity, we made casts of the anatomy by injecting an acrylic resin into the area. We then prepared paraffin sections to determine the distribution of the NALT and mucous cells. The mucous gland was clearly seen in the mucosal epithelium of the nasal cavity, suggesting that the pathway along the nasal cavity develops a nonspecific immune system to deal with large foreign substances, such as bacteria, using mucins that are secreted from the mucous glands. Hence, there is not only a physical barrier but also an antibacterial activity. Unlike in other animals, morphologically, the nasolacrimal duct in chicken becomes the ventral nasal meatus and opens into the choanae in the caudal portion of the nasal cavity. NALT was prominently present in the lamina propria of the ventral nasal meatus, suggesting the presence of a specific immune system protecting against avian viruses. Thus, responses to vaccine stimulation could be developed from tissues along the pathway of the ventral nasal meatus via the nasolacrimal duct running from the punctum. These morphological studies suggest that the instillation of eye drops could be used as an efficient vaccination method for avoiding respiratory diseases. |
| first_indexed | 2024-03-13T08:47:25Z |
| format | Article |
| id | doaj.art-ca516bfd85054726bf2406d799b05c7e |
| institution | Directory Open Access Journal |
| issn | 1346-7395 1349-0486 |
| language | English |
| last_indexed | 2024-03-13T08:47:25Z |
| publishDate | 2020-10-01 |
| publisher | Japan Poultry Science Association |
| record_format | Article |
| series | The Journal of Poultry Science |
| spelling | doaj.art-ca516bfd85054726bf2406d799b05c7e2023-05-30T01:08:01ZengJapan Poultry Science AssociationThe Journal of Poultry Science1346-73951349-04862020-10-0157430330910.2141/jpsa.0190091jpsaThree-Dimensional Analysis of the Nasolacrimal Duct and Nasal Cavity and Arrangement of Mucosal Tissue in ChickensTakafumi Watanabe0Naoki Takahashi1Jun Minaguchi2Ayaka Mochizuki3Kohzy Hiramatsu4Laboratory of Veterinary Anatomy, School of Veterinary Medicine, Rakuno Gakuen UniversityLaboratory of Veterinary Anatomy, School of Veterinary Medicine, Rakuno Gakuen UniversityLaboratory of Veterinary Anatomy, School of Veterinary Medicine, Rakuno Gakuen UniversityLaboratory of Animal Functional Anatomy (LAFA), Faculty of Agriculture, Shinshu UniversityLaboratory of Animal Functional Anatomy (LAFA), Faculty of Agriculture, Shinshu UniversityThe nasal mucosa plays an important role in the immune system, with nasal mucous cells secreting mucin that, along with pili, exclude foreign substances from intervening. Nasal mucosal-associated lymphoid tissue (NALT), present in the nasal lamina propria, acts as a local immune system. In birds, the Harderian gland in the orbit also plays an important role in the local immune system. In this study, we analyzed the pathway from the nasolacrimal duct to the nasal cavity in chickens and the distribution of the nasal mucous cells responsible for defense mechanisms against pathogens. To determine the three-dimensional structure of the pathway from the nasolacrimal duct to the nasal cavity, we made casts of the anatomy by injecting an acrylic resin into the area. We then prepared paraffin sections to determine the distribution of the NALT and mucous cells. The mucous gland was clearly seen in the mucosal epithelium of the nasal cavity, suggesting that the pathway along the nasal cavity develops a nonspecific immune system to deal with large foreign substances, such as bacteria, using mucins that are secreted from the mucous glands. Hence, there is not only a physical barrier but also an antibacterial activity. Unlike in other animals, morphologically, the nasolacrimal duct in chicken becomes the ventral nasal meatus and opens into the choanae in the caudal portion of the nasal cavity. NALT was prominently present in the lamina propria of the ventral nasal meatus, suggesting the presence of a specific immune system protecting against avian viruses. Thus, responses to vaccine stimulation could be developed from tissues along the pathway of the ventral nasal meatus via the nasolacrimal duct running from the punctum. These morphological studies suggest that the instillation of eye drops could be used as an efficient vaccination method for avoiding respiratory diseases.https://www.jstage.jst.go.jp/article/jpsa/57/4/57_0190091/_html/-char/enchickennasal cavitynasolacrimal ductvaccination |
| spellingShingle | Takafumi Watanabe Naoki Takahashi Jun Minaguchi Ayaka Mochizuki Kohzy Hiramatsu Three-Dimensional Analysis of the Nasolacrimal Duct and Nasal Cavity and Arrangement of Mucosal Tissue in Chickens The Journal of Poultry Science chicken nasal cavity nasolacrimal duct vaccination |
| title | Three-Dimensional Analysis of the Nasolacrimal Duct and Nasal Cavity and Arrangement of Mucosal Tissue in Chickens |
| title_full | Three-Dimensional Analysis of the Nasolacrimal Duct and Nasal Cavity and Arrangement of Mucosal Tissue in Chickens |
| title_fullStr | Three-Dimensional Analysis of the Nasolacrimal Duct and Nasal Cavity and Arrangement of Mucosal Tissue in Chickens |
| title_full_unstemmed | Three-Dimensional Analysis of the Nasolacrimal Duct and Nasal Cavity and Arrangement of Mucosal Tissue in Chickens |
| title_short | Three-Dimensional Analysis of the Nasolacrimal Duct and Nasal Cavity and Arrangement of Mucosal Tissue in Chickens |
| title_sort | three dimensional analysis of the nasolacrimal duct and nasal cavity and arrangement of mucosal tissue in chickens |
| topic | chicken nasal cavity nasolacrimal duct vaccination |
| url | https://www.jstage.jst.go.jp/article/jpsa/57/4/57_0190091/_html/-char/en |
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