Demographic and clinical characteristics of chikungunya patients from six Colombian cities, 2014–2015
AbstractIn 2014, the chikungunya virus reached Colombia for the first time, resulting in a nationwide epidemic. The objective of this study was to describe the demographics and clinical characteristics of suspected chikungunya cases. Chikungunya infection was confirmed by enzyme-linked immunosorbent...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2019-01-01
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| Series: | Emerging Microbes and Infections |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/22221751.2019.1678366 |
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| author | Juan C. Rueda Ana M. Santos Jose-Ignacio Angarita Rodrigo B. Giraldo Eugenia-Lucia Saldarriaga Jesús Giovanny Ballesteros Muñoz Elías Forero Hugo Valencia Francisco Somoza Daniel Martin-Arsanios Elias-Josué Quintero Viviana Reyes-Martinez Diana Padilla Francy M. Cuervo Ingris Peláez-Ballestas Mario H. Cardiel Paula X. Pavía John Londono |
| author_facet | Juan C. Rueda Ana M. Santos Jose-Ignacio Angarita Rodrigo B. Giraldo Eugenia-Lucia Saldarriaga Jesús Giovanny Ballesteros Muñoz Elías Forero Hugo Valencia Francisco Somoza Daniel Martin-Arsanios Elias-Josué Quintero Viviana Reyes-Martinez Diana Padilla Francy M. Cuervo Ingris Peláez-Ballestas Mario H. Cardiel Paula X. Pavía John Londono |
| author_sort | Juan C. Rueda |
| collection | DOAJ |
| description | AbstractIn 2014, the chikungunya virus reached Colombia for the first time, resulting in a nationwide epidemic. The objective of this study was to describe the demographics and clinical characteristics of suspected chikungunya cases. Chikungunya infection was confirmed by enzyme-linked immunosorbent assay and 548 patients where included in the study. Of these patients, 295 were positive for antibodies against chikungunya (53.8%), and 27.6% (151/295) were symptomatic for chikungunya infection, with a symptomatic:asymptomatic ratio of 1.04:1. Factors associated with infection included low income and low socio-economic strata (odds ratio [OR]: 1.8; 95% confidence interval [CI]: 1.0–3.2, p = 0.003 and OR: 2.1; CI: 1.3–3.4, p = 0.002, respectively). Confirmed symptomatic cases were associated with symmetric arthritis (OR: 11.7; CI: 6.0–23.0, p < 0.001) of ankles (OR: 8.5; CI: 3.5–20.9, p < 0.001), hands (OR: 8.5; CI: 3.5–20.9, p < 0.001), feet (OR: 6.5; CI: 2.8–15.3, p < 0.001), and wrists (OR: 17.3; CI: 2.3–130.5, p < 0.001). Our study showed that poverty is associated with chikungunya infection. Public health strategies to prevent and control chikungunya should focus on poorer communities that are more vulnerable to infection. The rate of asymptomatic infections among confirmed cases was 48.8%. However, those with symptoms displayed a characteristic rheumatic clinical picture, which could help differentiate chikungunya infection from other endemic viral diseases. |
| first_indexed | 2024-03-08T21:59:24Z |
| format | Article |
| id | doaj.art-ca532ede8f434cd6948dfbb35593b32a |
| institution | Directory Open Access Journal |
| issn | 2222-1751 |
| language | English |
| last_indexed | 2024-03-08T21:59:24Z |
| publishDate | 2019-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Emerging Microbes and Infections |
| spelling | doaj.art-ca532ede8f434cd6948dfbb35593b32a2023-12-19T16:09:58ZengTaylor & Francis GroupEmerging Microbes and Infections2222-17512019-01-01811490150010.1080/22221751.2019.1678366Demographic and clinical characteristics of chikungunya patients from six Colombian cities, 2014–2015Juan C. Rueda0Ana M. Santos1Jose-Ignacio Angarita2Rodrigo B. Giraldo3Eugenia-Lucia Saldarriaga4Jesús Giovanny Ballesteros Muñoz5Elías Forero6Hugo Valencia7Francisco Somoza8Daniel Martin-Arsanios9Elias-Josué Quintero10Viviana Reyes-Martinez11Diana Padilla12Francy M. Cuervo13Ingris Peláez-Ballestas14Mario H. Cardiel15Paula X. Pavía16John Londono17Biosciences Doctoral Programme, Faculty of Medicine and Engineering, Universidad de La Sabana, Chía, ColombiaGrupo Espondiloartropatías, Department of Rheumatology, Universidad de La Sabana, Chía, ColombiaGrupo Espondiloartropatías, Department of Rheumatology, Universidad de La Sabana, Chía, ColombiaGrupo Espondiloartropatías, Department of Rheumatology, Universidad de La Sabana, Chía, ColombiaGrupo Espondiloartropatías, Department of Rheumatology, Universidad de La Sabana, Chía, ColombiaDepartment of Rheumatology, Hospital Militar Central, Bogotá, ColombiaDepartment of Rheumatology and Internal Medicine, Universidad del Norte, Barranquilla, ColombiaGrupo Espondiloartropatías, Department of Rheumatology, Universidad de La Sabana, Chía, ColombiaGrupo Espondiloartropatías, Department of Rheumatology, Universidad de La Sabana, Chía, ColombiaGrupo Espondiloartropatías, Department of Rheumatology, Universidad de La Sabana, Chía, ColombiaGrupo Espondiloartropatías, Department of Rheumatology, Universidad de La Sabana, Chía, ColombiaGrupo Espondiloartropatías, Department of Rheumatology, Universidad de La Sabana, Chía, ColombiaGrupo Espondiloartropatías, Department of Rheumatology, Universidad de La Sabana, Chía, ColombiaGrupo Espondiloartropatías, Department of Rheumatology, Universidad de La Sabana, Chía, ColombiaRheumatology Unit, Hospital General de México “Doctor Eduardo Liceaga”, Mexico City, MexicoCentro de Investigación Clínica de Morelia SC, Morelia, MexicoUnidad de Investigación Científica, Hospital Militar Central, Bogotá, ColombiaGrupo Espondiloartropatías, Department of Rheumatology, Universidad de La Sabana, Chía, ColombiaAbstractIn 2014, the chikungunya virus reached Colombia for the first time, resulting in a nationwide epidemic. The objective of this study was to describe the demographics and clinical characteristics of suspected chikungunya cases. Chikungunya infection was confirmed by enzyme-linked immunosorbent assay and 548 patients where included in the study. Of these patients, 295 were positive for antibodies against chikungunya (53.8%), and 27.6% (151/295) were symptomatic for chikungunya infection, with a symptomatic:asymptomatic ratio of 1.04:1. Factors associated with infection included low income and low socio-economic strata (odds ratio [OR]: 1.8; 95% confidence interval [CI]: 1.0–3.2, p = 0.003 and OR: 2.1; CI: 1.3–3.4, p = 0.002, respectively). Confirmed symptomatic cases were associated with symmetric arthritis (OR: 11.7; CI: 6.0–23.0, p < 0.001) of ankles (OR: 8.5; CI: 3.5–20.9, p < 0.001), hands (OR: 8.5; CI: 3.5–20.9, p < 0.001), feet (OR: 6.5; CI: 2.8–15.3, p < 0.001), and wrists (OR: 17.3; CI: 2.3–130.5, p < 0.001). Our study showed that poverty is associated with chikungunya infection. Public health strategies to prevent and control chikungunya should focus on poorer communities that are more vulnerable to infection. The rate of asymptomatic infections among confirmed cases was 48.8%. However, those with symptoms displayed a characteristic rheumatic clinical picture, which could help differentiate chikungunya infection from other endemic viral diseases.https://www.tandfonline.com/doi/10.1080/22221751.2019.1678366Chikungunya virusColombiaEpidemicSouth AmericaArbovirus |
| spellingShingle | Juan C. Rueda Ana M. Santos Jose-Ignacio Angarita Rodrigo B. Giraldo Eugenia-Lucia Saldarriaga Jesús Giovanny Ballesteros Muñoz Elías Forero Hugo Valencia Francisco Somoza Daniel Martin-Arsanios Elias-Josué Quintero Viviana Reyes-Martinez Diana Padilla Francy M. Cuervo Ingris Peláez-Ballestas Mario H. Cardiel Paula X. Pavía John Londono Demographic and clinical characteristics of chikungunya patients from six Colombian cities, 2014–2015 Emerging Microbes and Infections Chikungunya virus Colombia Epidemic South America Arbovirus |
| title | Demographic and clinical characteristics of chikungunya patients from six Colombian cities, 2014–2015 |
| title_full | Demographic and clinical characteristics of chikungunya patients from six Colombian cities, 2014–2015 |
| title_fullStr | Demographic and clinical characteristics of chikungunya patients from six Colombian cities, 2014–2015 |
| title_full_unstemmed | Demographic and clinical characteristics of chikungunya patients from six Colombian cities, 2014–2015 |
| title_short | Demographic and clinical characteristics of chikungunya patients from six Colombian cities, 2014–2015 |
| title_sort | demographic and clinical characteristics of chikungunya patients from six colombian cities 2014 2015 |
| topic | Chikungunya virus Colombia Epidemic South America Arbovirus |
| url | https://www.tandfonline.com/doi/10.1080/22221751.2019.1678366 |
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