Actin-binding protein regulation by microRNAs as a novel microbial strategy to modulate phagocytosis by host cells: the case of N-Wasp and miR-142-3p

Actin-binding protein regulation by microRNAs as a novel microbial strategy to modulate phagocytosis by host cells: the case of N-Wasp and miR-142-3p

Mycobacterium tuberculosis (Mtb) is a successful intracellular pathogen that thrives in macrophages (Mφs). There is a need to better understand how Mtb hijacks cellular processes like phagolysosome biogenesis, a classical pathogenesis determinant. A central feature to this microbial strategy is the...

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Bibliographic Details
Main Authors: Paulo eBettencourt, Sabrina eMarion, David ePires, Leonor eSantos, Claire eLastrucci, Nuno eCarmo, Jonathon eBlake, Vladimir eBenes, Gareth eGriffiths, Olivier eNeyrolles, Geanncarlo eLugo-Villarino, Elsa eAnes
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-06-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Phagocytosis
Tuberculosis
miRNA
macrophage
mir-142-3p
N-Wasp
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2013.00019/full

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