CXCR6+ Tumor-Associated Macrophages Identify Immunosuppressive Colon Cancer Patients with Poor Prognosis but Favorable Response to Adjuvant Chemotherapy

CXCR6+ Tumor-Associated Macrophages Identify Immunosuppressive Colon Cancer Patients with Poor Prognosis but Favorable Response to Adjuvant Chemotherapy

We explored the infiltration and prognostic value of CXCR6+TAMs in all stages of colon cancer (CC) patients and assessed predictive ability as a biomarker for different ACT regimens among high-risk stage II and stage III patients in both primary and validation cohorts. Two independent cohorts of 360...

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Bibliographic Details
Main Authors: Jiang Chang, Songbin Lin, Yihao Mao, Yuqiu Xu, Zhiyuan Zhang, Qi Wu, Yijiao Chen, Ye Wei, Qingyang Feng, Jianmin Xu
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Cancers
Subjects:
tumor-associated macrophages
colon cancer
adjuvant chemotherapy
immune microenvironment
Online Access:https://www.mdpi.com/2072-6694/14/19/4646

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