Changes in cultured endothelial cell glycosaminoglycans under hyperglycemic conditions and the effect of insulin and heparin

Changes in cultured endothelial cell glycosaminoglycans under hyperglycemic conditions and the effect of insulin and heparin

<p>Abstract</p> <p>Background</p> <p>Heparan sulfate proteoglycans (HSPGs) contain glycosaminoglycan (GAG) chains made primarily of heparan sulfate (HS). Hyperglycemia in diabetes leads to endothelial injury and nephropathy, retinopathy and atherosclerosis. Decreased HS...

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Bibliografski detalji
Glavni autori: Linhardt Robert J, Xie Jin, Zhang Fuming, Han Juying, Hiebert Linda M
Format: Članak
Jezik:English
Izdano: BMC 2009-08-01
Serija:Cardiovascular Diabetology
Online pristup:http://www.cardiab.com/content/8/1/46

Internet

http://www.cardiab.com/content/8/1/46

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