Inhibitory Effect of Aqueous Salvia officinalis’s leaves in the Growth of Candida albicans from Infected Women with Vaginal Candidiasis

Background: Salvia officinalis is a plant belong to Labiatae family .The common name of Salvia is sage which mean save. The leaves of Salvia have special oil which is effective against filamentous fungi and yeasts such as Candida albicans which is the causative agent of vaginal candidiasis in women...

Full description

Bibliographic Details
Main Authors: Rusul Mohammad jasim, Israa Mohammad Abd AL-khaliq
Format: Article
Language:English
Published: University of Baghdad/ Al-Kindy College of Medicine 2011-06-01
Series:مجله كليه طب الكندي
Subjects:
Online Access:https://jkmc.uobaghdad.edu.iq/index.php/MEDICAL/article/view/666
_version_ 1798002106099040256
author Rusul Mohammad jasim
Israa Mohammad Abd AL-khaliq
author_facet Rusul Mohammad jasim
Israa Mohammad Abd AL-khaliq
author_sort Rusul Mohammad jasim
collection DOAJ
description Background: Salvia officinalis is a plant belong to Labiatae family .The common name of Salvia is sage which mean save. The leaves of Salvia have special oil which is effective against filamentous fungi and yeasts such as Candida albicans which is the causative agent of vaginal candidiasis in women Methods. Cultures from 50 swabs of Candida albicans isolated from vagina of 70 patient women who complains from vaginal problems, their ages (24-43) years from Central City Hospital during Febreoury 2009 to April 2009 were cultured on Sabouraud Dextrose Agar (SDA) .Nystatin was used as positive reference standard to determine the sensitivity of this fungus . and less this concentration there was no minimum inhibition for the Candida Results: The aqueous extract of Salvia officinalis at various concentrations inhibited the growth of C. Albicans . This inhibitions reached to a maximum of 100% for extract at 25 mg / ml and the minimum inhibition was 170 mm at 15 mg /ml for the extract . While the minimum and maximum inhibition for nystatin was at 50 μg/ml,and less concentration. There was no minimum inhibition for the Candida Conclutions : The findings provide support for the use of this plant in traditional medicine for fungal infections especially against candidiasis .
first_indexed 2024-04-11T11:46:58Z
format Article
id doaj.art-ca55cace17ee4648bc6394d4fece441a
institution Directory Open Access Journal
issn 1810-9543
2521-4365
language English
last_indexed 2024-04-11T11:46:58Z
publishDate 2011-06-01
publisher University of Baghdad/ Al-Kindy College of Medicine
record_format Article
series مجله كليه طب الكندي
spelling doaj.art-ca55cace17ee4648bc6394d4fece441a2022-12-22T04:25:32ZengUniversity of Baghdad/ Al-Kindy College of Medicineمجله كليه طب الكندي1810-95432521-43652011-06-0171Inhibitory Effect of Aqueous Salvia officinalis’s leaves in the Growth of Candida albicans from Infected Women with Vaginal CandidiasisRusul Mohammad jasim0Israa Mohammad Abd AL-khaliq10000 Background: Salvia officinalis is a plant belong to Labiatae family .The common name of Salvia is sage which mean save. The leaves of Salvia have special oil which is effective against filamentous fungi and yeasts such as Candida albicans which is the causative agent of vaginal candidiasis in women Methods. Cultures from 50 swabs of Candida albicans isolated from vagina of 70 patient women who complains from vaginal problems, their ages (24-43) years from Central City Hospital during Febreoury 2009 to April 2009 were cultured on Sabouraud Dextrose Agar (SDA) .Nystatin was used as positive reference standard to determine the sensitivity of this fungus . and less this concentration there was no minimum inhibition for the Candida Results: The aqueous extract of Salvia officinalis at various concentrations inhibited the growth of C. Albicans . This inhibitions reached to a maximum of 100% for extract at 25 mg / ml and the minimum inhibition was 170 mm at 15 mg /ml for the extract . While the minimum and maximum inhibition for nystatin was at 50 μg/ml,and less concentration. There was no minimum inhibition for the Candida Conclutions : The findings provide support for the use of this plant in traditional medicine for fungal infections especially against candidiasis . https://jkmc.uobaghdad.edu.iq/index.php/MEDICAL/article/view/666Antifungal activityCandida albicans,NystatinSalvia officinalis,Vaginal candidiasis
spellingShingle Rusul Mohammad jasim
Israa Mohammad Abd AL-khaliq
Inhibitory Effect of Aqueous Salvia officinalis’s leaves in the Growth of Candida albicans from Infected Women with Vaginal Candidiasis
مجله كليه طب الكندي
Antifungal activity
Candida albicans
,Nystatin
Salvia officinalis,
Vaginal candidiasis
title Inhibitory Effect of Aqueous Salvia officinalis’s leaves in the Growth of Candida albicans from Infected Women with Vaginal Candidiasis
title_full Inhibitory Effect of Aqueous Salvia officinalis’s leaves in the Growth of Candida albicans from Infected Women with Vaginal Candidiasis
title_fullStr Inhibitory Effect of Aqueous Salvia officinalis’s leaves in the Growth of Candida albicans from Infected Women with Vaginal Candidiasis
title_full_unstemmed Inhibitory Effect of Aqueous Salvia officinalis’s leaves in the Growth of Candida albicans from Infected Women with Vaginal Candidiasis
title_short Inhibitory Effect of Aqueous Salvia officinalis’s leaves in the Growth of Candida albicans from Infected Women with Vaginal Candidiasis
title_sort inhibitory effect of aqueous salvia officinalis s leaves in the growth of candida albicans from infected women with vaginal candidiasis
topic Antifungal activity
Candida albicans
,Nystatin
Salvia officinalis,
Vaginal candidiasis
url https://jkmc.uobaghdad.edu.iq/index.php/MEDICAL/article/view/666
work_keys_str_mv AT rusulmohammadjasim inhibitoryeffectofaqueoussalviaofficinalissleavesinthegrowthofcandidaalbicansfrominfectedwomenwithvaginalcandidiasis
AT israamohammadabdalkhaliq inhibitoryeffectofaqueoussalviaofficinalissleavesinthegrowthofcandidaalbicansfrominfectedwomenwithvaginalcandidiasis