4‐Aminopyridine promotes functional recovery and remyelination in acute peripheral nerve injury

Abstract Traumatic peripheral nerve damage is a major medical problem without effective treatment options. In repurposing studies on 4‐aminopyridine (4‐AP), a potassium channel blocker that provides symptomatic relief in some chronic neurological afflictions, we discovered this agent offers signific...

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Bibliographic Details
Main Authors: Kuang‐Ching Tseng, Haiyan Li, Andrew Clark, Leigh Sundem, Michael Zuscik, Mark Noble, John Elfar
Format: Article
Language:English
Published: Springer Nature 2016-12-01
Series:EMBO Molecular Medicine
Subjects:
Online Access:https://doi.org/10.15252/emmm.201506035