Metabolic reprogramming of the urea cycle pathway in experimental pulmonary arterial hypertension rats induced by monocrotaline

Metabolic reprogramming of the urea cycle pathway in experimental pulmonary arterial hypertension rats induced by monocrotaline

Abstract Background Pulmonary arterial hypertension (PAH) is a rare systemic disorder associated with considerable metabolic dysfunction. Although enormous metabolomic studies on PAH have been emerging, research remains lacking on metabolic reprogramming in experimental PAH models. We aim to evaluat...

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Bibliographic Details
Main Authors: Hai-Kuo Zheng, Jun-Han Zhao, Yi Yan, Tian-Yu Lian, Jue Ye, Xiao-Jian Wang, Zhe Wang, Zhi-Cheng Jing, Yang-Yang He, Ping Yang
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Respiratory Research
Subjects:
Pulmonary arterial hypertension
Metabolomics
Urea cycle
Pathway
Biomarker
Online Access:http://link.springer.com/article/10.1186/s12931-018-0800-5

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