The PTPN22 locus and rheumatoid arthritis: no evidence for an effect on risk independent of Arg620Trp.

The PTPN22 locus and rheumatoid arthritis: no evidence for an effect on risk independent of Arg620Trp.

The Trp(620) allotype of PTPN22 confers susceptibility to rheumatoid arthritis (RA) and certain other classical autoimmune diseases. There has been a report of other variants within the PTPN22 locus that alter risk of RA; protective haplotype '5', haplotype group '6-10' and susce...

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Bibliographic Details
Main Authors: Wan R Wan Taib, Deborah J Smyth, Marilyn E Merriman, Nicola Dalbeth, Peter J Gow, Andrew A Harrison, John Highton, Peter B B Jones, Lisa Stamp, Sophia Steer, John A Todd, Tony R Merriman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2958827?pdf=render

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