Differential regulation of lineage commitment in human and mouse primed pluripotent stem cells by the nucleosome remodelling and deacetylation complex

Differential regulation of lineage commitment in human and mouse primed pluripotent stem cells by the nucleosome remodelling and deacetylation complex

Differentiation of mammalian pluripotent cells involves large-scale changes in transcription and, among the molecules that orchestrate these changes, chromatin remodellers are essential to initiate, establish and maintain a new gene regulatory network. The Nucleosome Remodelling and Deacetylation (N...

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Bibliographic Details
Main Authors: Ramy Ragheb, Sarah Gharbi, Julie Cramard, Oluwaseun Ogundele, Susan L. Kloet, Thomas Burgold, Michiel Vermeulen, Nicola Reynolds, Brian Hendrich
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:Stem Cell Research
Subjects:
Pluripotency
Chromatin
Lineage commitment
Transcriptomics
iPS cell
epiStem cell
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506120301689

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