Linking acetylated α-Tubulin redistribution to α-Synuclein pathology in brain of Parkinson’s disease patients

Linking acetylated α-Tubulin redistribution to α-Synuclein pathology in brain of Parkinson’s disease patients

Abstract Highly specialized microtubules in neurons are crucial to both health and disease of the nervous system, and their properties are strictly regulated by different post-translational modifications, including α-Tubulin acetylation. An imbalance in the levels of acetylated α-Tubulin has been re...

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Bibliographic Details
Main Authors: Samanta Mazzetti, Federica Giampietro, Alessandra Maria Calogero, Huseyin Berkcan Isilgan, Gloria Gagliardi, Chiara Rolando, Francesca Cantele, Miriam Ascagni, Manuela Bramerio, Giorgio Giaccone, Ioannis Ugo Isaias, Gianni Pezzoli, Graziella Cappelletti
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-023-00607-9

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