Enhanced production of terrein in marine-derived Aspergillus terreus by refactoring both global and pathway-specific transcription factors

Enhanced production of terrein in marine-derived Aspergillus terreus by refactoring both global and pathway-specific transcription factors

Abstract Background Terrein, a major secondary metabolite from Aspergillus terreus, shows great potentials in biomedical and agricultural applications. However, the low fermentation yield of terrein in wild A. terreus strains limits its industrial applications. Results Here, we constructed a cell fa...

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Bibliographic Details
Main Authors: Guangshan Yao, Xinfeng Bai, Bingxin Zhang, Lu Wang, Songbiao Chen, Zonghua Wang
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Microbial Cell Factories
Subjects:
Terrein
Aspergillus terreus cell factory
Transcription factor
StuA
TerR, secondary metabolism
Online Access:https://doi.org/10.1186/s12934-022-01859-5

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