Codon choice directs constitutive mRNA levels in trypanosomes

Codon choice directs constitutive mRNA levels in trypanosomes

Selective transcription of individual protein coding genes does not occur in trypanosomes and the cellular copy number of each mRNA must be determined post-transcriptionally. Here, we provide evidence that codon choice directs the levels of constitutively expressed mRNAs. First, a novel codon usage...

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Bibliographic Details
Main Authors: Janaina de Freitas Nascimento, Steven Kelly, Jack Sunter, Mark Carrington
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-03-01
Series:eLife
Subjects:
codon choice
mRNA expression
trypanosome
Trypanosome brucei
Online Access:https://elifesciences.org/articles/32467

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