Differential transcriptomic alterations in nasal versus lung tissue of acrolein-exposed rats

Differential transcriptomic alterations in nasal versus lung tissue of acrolein-exposed rats

Introduction: Acrolein is a significant component of anthropogenic and wildfire emissions, as well as cigarette smoke. Although acrolein primarily deposits in the upper respiratory tract upon inhalation, patterns of site-specific injury in nasal versus pulmonary tissues are not well characterized. T...

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Bibliographic Details
Main Authors:	Devin I. Alewel, Thomas W. Jackson, Katherine M. Rentschler, Mette C. Schladweiler, Anna Astriab-Fisher, Stephen H. Gavett, Paul A. Evansky, Urmila P. Kodavanti
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-11-01
Series:	Frontiers in Toxicology
Subjects:	acrolein air pollution nose lung glucocorticoids cytokines
Online Access:	https://www.frontiersin.org/articles/10.3389/ftox.2023.1280230/full

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