Anaesthetic management of bilateral hand transplantation: A case series

Background: Bilateral hand transplantation is a rare surgery being considered for patients with bilateral upper limb loss. The procedure, though not lifesaving, is a life-altering procedure with inherent risks. Aims and Objectives: The anaesthetic management of these patients is technically challe...

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Main Authors: Nandhini Joseph, Niranjan Kumar Sasikumar, Sunil Rajan, Pulak Tosh, Jerry Paul, Lakshmi Kumar
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:Hamdan Medical Journal
Subjects:
Online Access:http://www.hamdanjournal.org/article.asp?issn=2227-2437;year=2023;volume=16;issue=2;spage=106;epage=110;aulast=Joseph
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author Nandhini Joseph
Niranjan Kumar Sasikumar
Sunil Rajan
Pulak Tosh
Jerry Paul
Lakshmi Kumar
author_facet Nandhini Joseph
Niranjan Kumar Sasikumar
Sunil Rajan
Pulak Tosh
Jerry Paul
Lakshmi Kumar
author_sort Nandhini Joseph
collection DOAJ
description Background: Bilateral hand transplantation is a rare surgery being considered for patients with bilateral upper limb loss. The procedure, though not lifesaving, is a life-altering procedure with inherent risks. Aims and Objectives: The anaesthetic management of these patients is technically challenging, with huge fluid shifts, blood loss, haemodynamic instability and hypothermia. We aimed to find out the major perioperative concerns and their management strategies during bilateral hand transplantation surgery by retrospectively analysing the anaesthetic management of six such cases. Materials and Methods: A retrospective study of the anaesthetic management of six patients who underwent bilateral hand transplants in our institute, and their post-operative outcomes is described. Results: All cases were performed under general anaesthesia with supplemental brachial plexus block. The major intraoperative concerns were immunosuppression, massive blood loss and fluid replacement, haemodynamic instability, reperfusion injury and hypothermia. Vasopressors were used in four out of the six patients with no major effect on the graft survival outcome. These patients have been followed up for a time period varying from 6 months to 3 years and have been successfully rehabilitated back to normal life. Conclusion: Bilateral hand transplants can be safely performed under general anaesthesia with supplemental brachial plexus block. The anaesthetic management of these patients is challenging and requires a structured approach with good facilities for perioperative management.
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spelling doaj.art-ca6cb9a201a340fd9700a0739bf3d19f2023-07-21T14:44:41ZengWolters Kluwer Medknow PublicationsHamdan Medical Journal2227-24372227-247X2023-01-0116210611010.4103/hmj.hmj_98_22Anaesthetic management of bilateral hand transplantation: A case seriesNandhini JosephNiranjan Kumar SasikumarSunil RajanPulak ToshJerry PaulLakshmi KumarBackground: Bilateral hand transplantation is a rare surgery being considered for patients with bilateral upper limb loss. The procedure, though not lifesaving, is a life-altering procedure with inherent risks. Aims and Objectives: The anaesthetic management of these patients is technically challenging, with huge fluid shifts, blood loss, haemodynamic instability and hypothermia. We aimed to find out the major perioperative concerns and their management strategies during bilateral hand transplantation surgery by retrospectively analysing the anaesthetic management of six such cases. Materials and Methods: A retrospective study of the anaesthetic management of six patients who underwent bilateral hand transplants in our institute, and their post-operative outcomes is described. Results: All cases were performed under general anaesthesia with supplemental brachial plexus block. The major intraoperative concerns were immunosuppression, massive blood loss and fluid replacement, haemodynamic instability, reperfusion injury and hypothermia. Vasopressors were used in four out of the six patients with no major effect on the graft survival outcome. These patients have been followed up for a time period varying from 6 months to 3 years and have been successfully rehabilitated back to normal life. Conclusion: Bilateral hand transplants can be safely performed under general anaesthesia with supplemental brachial plexus block. The anaesthetic management of these patients is challenging and requires a structured approach with good facilities for perioperative management.http://www.hamdanjournal.org/article.asp?issn=2227-2437;year=2023;volume=16;issue=2;spage=106;epage=110;aulast=Josephcomposite tissue allotransplantationgraft survivalhand transplantationvascularised composite allotransplantation
spellingShingle Nandhini Joseph
Niranjan Kumar Sasikumar
Sunil Rajan
Pulak Tosh
Jerry Paul
Lakshmi Kumar
Anaesthetic management of bilateral hand transplantation: A case series
Hamdan Medical Journal
composite tissue allotransplantation
graft survival
hand transplantation
vascularised composite allotransplantation
title Anaesthetic management of bilateral hand transplantation: A case series
title_full Anaesthetic management of bilateral hand transplantation: A case series
title_fullStr Anaesthetic management of bilateral hand transplantation: A case series
title_full_unstemmed Anaesthetic management of bilateral hand transplantation: A case series
title_short Anaesthetic management of bilateral hand transplantation: A case series
title_sort anaesthetic management of bilateral hand transplantation a case series
topic composite tissue allotransplantation
graft survival
hand transplantation
vascularised composite allotransplantation
url http://www.hamdanjournal.org/article.asp?issn=2227-2437;year=2023;volume=16;issue=2;spage=106;epage=110;aulast=Joseph
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AT sunilrajan anaestheticmanagementofbilateralhandtransplantationacaseseries
AT pulaktosh anaestheticmanagementofbilateralhandtransplantationacaseseries
AT jerrypaul anaestheticmanagementofbilateralhandtransplantationacaseseries
AT lakshmikumar anaestheticmanagementofbilateralhandtransplantationacaseseries