Case Report: Tracheal infiltration with wheezing revealing Hodgkin's disease [version 2; peer review: 2 approved]
Hodgkin's disease with an initial tracheobronchial involvement is not common. The symptoms might be misleading, resulting in a diagnosis delay. We report the case of a 38-year-old woman with a one-month history of wheezing associated with a dry cough. The physical examination revealed a good ge...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
F1000 Research Ltd
2023-09-01
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| Series: | F1000Research |
| Subjects: | |
| Online Access: | https://f1000research.com/articles/12-404/v2 |
| _version_ | 1797683296747913216 |
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| author | Fehmi Msadek Moetemri Zied Chiraz Aichaouia Ghedira Hela Nouha boubaker Samira Mhamdi Chaabane Mariem Selsabil Daboussi Asma Saidane |
| author_facet | Fehmi Msadek Moetemri Zied Chiraz Aichaouia Ghedira Hela Nouha boubaker Samira Mhamdi Chaabane Mariem Selsabil Daboussi Asma Saidane |
| author_sort | Fehmi Msadek |
| collection | DOAJ |
| description | Hodgkin's disease with an initial tracheobronchial involvement is not common. The symptoms might be misleading, resulting in a diagnosis delay. We report the case of a 38-year-old woman with a one-month history of wheezing associated with a dry cough. The physical examination revealed a good general state of health, bilateral wheezing and supra-clavicular lymphadenopathy. The adenopathy biopsy's histopathology revealed Hodgkin lymphoma. The whole body FDG-PET scan was an important tool to assess the diagnosis as well as for the staging. The patient was treated with chemotherapy. Another unusual aspect is the tracheobronchial metastasis confirmed by a bronchial biopsy. Thus, our patient was put on a second-line chemotherapy. She died one year after the initial diagnosis. To conclude, it is an atypical clinical presentation of an Hodgkin lymphoma with a tracheobronchial relapse. It should be considered in the differential diagnosis of asthma or a tracheal tumor. |
| first_indexed | 2024-03-12T00:12:28Z |
| format | Article |
| id | doaj.art-ca6fd7281d8a48e29ef7c8414d2304b8 |
| institution | Directory Open Access Journal |
| issn | 2046-1402 |
| language | English |
| last_indexed | 2024-03-12T00:12:28Z |
| publishDate | 2023-09-01 |
| publisher | F1000 Research Ltd |
| record_format | Article |
| series | F1000Research |
| spelling | doaj.art-ca6fd7281d8a48e29ef7c8414d2304b82023-09-16T00:00:02ZengF1000 Research LtdF1000Research2046-14022023-09-0112155070Case Report: Tracheal infiltration with wheezing revealing Hodgkin's disease [version 2; peer review: 2 approved]Fehmi Msadek0Moetemri Zied1Chiraz Aichaouia2Ghedira Hela3Nouha boubaker4Samira Mhamdi5https://orcid.org/0000-0003-3284-426XChaabane Mariem6Selsabil Daboussi7https://orcid.org/0000-0001-7732-8643Asma Saidane8University of Tunis El Manar, Tunis, TunisiaUniversity of Tunis El Manar, Tunis, TunisiaUniversity of Tunis El Manar, Tunis, TunisiaUniversity of Tunis El Manar, Tunis, TunisiaPneumology Department, Military Hospital of Tunis, Tunisia, 1008, TunisiaUniversity of Tunis El Manar, Tunis, TunisiaPneumology Department, Military Hospital of Tunis, Tunisia, 1008, TunisiaUniversity of Tunis El Manar, Tunis, TunisiaPneumology Department, Military Hospital of Tunis, Tunisia, 1008, TunisiaHodgkin's disease with an initial tracheobronchial involvement is not common. The symptoms might be misleading, resulting in a diagnosis delay. We report the case of a 38-year-old woman with a one-month history of wheezing associated with a dry cough. The physical examination revealed a good general state of health, bilateral wheezing and supra-clavicular lymphadenopathy. The adenopathy biopsy's histopathology revealed Hodgkin lymphoma. The whole body FDG-PET scan was an important tool to assess the diagnosis as well as for the staging. The patient was treated with chemotherapy. Another unusual aspect is the tracheobronchial metastasis confirmed by a bronchial biopsy. Thus, our patient was put on a second-line chemotherapy. She died one year after the initial diagnosis. To conclude, it is an atypical clinical presentation of an Hodgkin lymphoma with a tracheobronchial relapse. It should be considered in the differential diagnosis of asthma or a tracheal tumor.https://f1000research.com/articles/12-404/v2Hodgkin’s disease wheezing trachea chemotherapyeng |
| spellingShingle | Fehmi Msadek Moetemri Zied Chiraz Aichaouia Ghedira Hela Nouha boubaker Samira Mhamdi Chaabane Mariem Selsabil Daboussi Asma Saidane Case Report: Tracheal infiltration with wheezing revealing Hodgkin's disease [version 2; peer review: 2 approved] F1000Research Hodgkin’s disease wheezing trachea chemotherapy eng |
| title | Case Report: Tracheal infiltration with wheezing revealing Hodgkin's disease [version 2; peer review: 2 approved] |
| title_full | Case Report: Tracheal infiltration with wheezing revealing Hodgkin's disease [version 2; peer review: 2 approved] |
| title_fullStr | Case Report: Tracheal infiltration with wheezing revealing Hodgkin's disease [version 2; peer review: 2 approved] |
| title_full_unstemmed | Case Report: Tracheal infiltration with wheezing revealing Hodgkin's disease [version 2; peer review: 2 approved] |
| title_short | Case Report: Tracheal infiltration with wheezing revealing Hodgkin's disease [version 2; peer review: 2 approved] |
| title_sort | case report tracheal infiltration with wheezing revealing hodgkin s disease version 2 peer review 2 approved |
| topic | Hodgkin’s disease wheezing trachea chemotherapy eng |
| url | https://f1000research.com/articles/12-404/v2 |
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