Propofol versus placebo (with rescue with ketamine) before less invasive surfactant administration: study protocol for a multicenter, double-blind, placebo controlled trial (PROLISA)

Propofol versus placebo (with rescue with ketamine) before less invasive surfactant administration: study protocol for a multicenter, double-blind, placebo controlled trial (PROLISA)

Abstract Background One major limitation for less invasive surfactant administration (LISA) is the difficulty in providing sedation before this procedure and the competitive risk of respiratory depression versus avoidance of intubation for most sedative or analgesic drugs used in this context. The o...

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Bibliographic Details
Main Authors: Marie Chevallier, Xavier Durrmeyer, Anne Ego, Thierry Debillon, The PROLISA Study Group
Format: Article
Language:English
Published: BMC 2020-05-01
Series:BMC Pediatrics
Subjects:
Less invasive surfactant administration
Sedation
Propofol
Ketamine
Randomized study
Online Access:http://link.springer.com/article/10.1186/s12887-020-02112-x

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