Predictors of COVID-19 vaccine uptake among adults in South Africa: multimethod evidence from a population-based longitudinal study

Background COVID-19 vaccine coverage remains low in many low and middle-income countries despite widespread access. To understand the dynamic decision-making process around vaccination and provide evidence for future vaccine promotion campaigns, we identified predictors of COVID-19 vaccine uptake am...

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Main Authors: Brendan Maughan-Brown, Alison M Buttenheim, Katherine Claire Eyal, Lindokuhle Njozela
Format: Article
Language:English
Published: BMJ Publishing Group 2023-08-01
Series:BMJ Global Health
Online Access:https://gh.bmj.com/content/8/8/e012433.full
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author Brendan Maughan-Brown
Alison M Buttenheim
Katherine Claire Eyal
Lindokuhle Njozela
author_facet Brendan Maughan-Brown
Alison M Buttenheim
Katherine Claire Eyal
Lindokuhle Njozela
author_sort Brendan Maughan-Brown
collection DOAJ
description Background COVID-19 vaccine coverage remains low in many low and middle-income countries despite widespread access. To understand the dynamic decision-making process around vaccination and provide evidence for future vaccine promotion campaigns, we identified predictors of COVID-19 vaccine uptake among South African adults, including those who did not believe in the vaccine’s safety or efficacy.Methods Data from two longitudinal telephone surveys in late 2021 and early 2022 of unvaccinated South African adults were used to model COVID-19 uptake. Predictors of interest informed by the theory of planned behaviour included vaccine attitudes and beliefs, social norms, perceived behavioural control and vaccine intentions. Responses to open-ended questions provided insights into key reasons for getting vaccinated.Results Among panel participants (n=1772), 19% reported being vaccinated between Survey 1 and Survey 2. Vaccine uptake was greater among participants who reported wanting to get vaccinated ‘as soon as possible’ (+27 percentage points, p<0.01). Vaccine uptake was greater among participants who believed that the vaccine is effective in preventing COVID-19 infection and/or death (+12 percentage points, p<0.01) and lower among those who believed that the vaccine is unsafe (−9 percentage points, p<0.01). Among participants who did not believe the vaccine is safe, living with someone already vaccinated against COVID-19 increased vaccine uptake (+6 percentage points, p<0.05). At Survey 1, the intention to get vaccinated as soon as possible was positively associated with perceived risk of illness from COVID-19 (+9.2 percentage points, p<0.05), the belief that most people in their area had been vaccinated (+7.0 percentage points, p<0.05) and living with someone already vaccinated against COVID-19 (+6.6 percentage points, p<0.05).Conclusion Study findings underscore the predictive power of intentions and of beliefs about disease risk, vaccine safety and vaccine efficacy. Social proof interventions hold promise for increasing vaccination intentions and overcoming concerns about vaccine safety.
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spelling doaj.art-ca76b7a023904ad6abfb4d858161cb992023-09-01T06:55:07ZengBMJ Publishing GroupBMJ Global Health2059-79082023-08-018810.1136/bmjgh-2023-012433Predictors of COVID-19 vaccine uptake among adults in South Africa: multimethod evidence from a population-based longitudinal studyBrendan Maughan-Brown0Alison M Buttenheim1Katherine Claire Eyal2Lindokuhle Njozela3Southern Africa Labour and Development Research Unit, University of Cape Town, Cape Town, South AfricaFamily and Community Health, University of Pennsylvania School of Nursing, Philadelphia, Pennsylvania, USASouthern Africa Labour and Development Research Unit, School of Economics, University of Cape Town, Cape Town, South AfricaSchool of Economics, University of Cape Town, Cape Town, South AfricaBackground COVID-19 vaccine coverage remains low in many low and middle-income countries despite widespread access. To understand the dynamic decision-making process around vaccination and provide evidence for future vaccine promotion campaigns, we identified predictors of COVID-19 vaccine uptake among South African adults, including those who did not believe in the vaccine’s safety or efficacy.Methods Data from two longitudinal telephone surveys in late 2021 and early 2022 of unvaccinated South African adults were used to model COVID-19 uptake. Predictors of interest informed by the theory of planned behaviour included vaccine attitudes and beliefs, social norms, perceived behavioural control and vaccine intentions. Responses to open-ended questions provided insights into key reasons for getting vaccinated.Results Among panel participants (n=1772), 19% reported being vaccinated between Survey 1 and Survey 2. Vaccine uptake was greater among participants who reported wanting to get vaccinated ‘as soon as possible’ (+27 percentage points, p<0.01). Vaccine uptake was greater among participants who believed that the vaccine is effective in preventing COVID-19 infection and/or death (+12 percentage points, p<0.01) and lower among those who believed that the vaccine is unsafe (−9 percentage points, p<0.01). Among participants who did not believe the vaccine is safe, living with someone already vaccinated against COVID-19 increased vaccine uptake (+6 percentage points, p<0.05). At Survey 1, the intention to get vaccinated as soon as possible was positively associated with perceived risk of illness from COVID-19 (+9.2 percentage points, p<0.05), the belief that most people in their area had been vaccinated (+7.0 percentage points, p<0.05) and living with someone already vaccinated against COVID-19 (+6.6 percentage points, p<0.05).Conclusion Study findings underscore the predictive power of intentions and of beliefs about disease risk, vaccine safety and vaccine efficacy. Social proof interventions hold promise for increasing vaccination intentions and overcoming concerns about vaccine safety.https://gh.bmj.com/content/8/8/e012433.full
spellingShingle Brendan Maughan-Brown
Alison M Buttenheim
Katherine Claire Eyal
Lindokuhle Njozela
Predictors of COVID-19 vaccine uptake among adults in South Africa: multimethod evidence from a population-based longitudinal study
BMJ Global Health
title Predictors of COVID-19 vaccine uptake among adults in South Africa: multimethod evidence from a population-based longitudinal study
title_full Predictors of COVID-19 vaccine uptake among adults in South Africa: multimethod evidence from a population-based longitudinal study
title_fullStr Predictors of COVID-19 vaccine uptake among adults in South Africa: multimethod evidence from a population-based longitudinal study
title_full_unstemmed Predictors of COVID-19 vaccine uptake among adults in South Africa: multimethod evidence from a population-based longitudinal study
title_short Predictors of COVID-19 vaccine uptake among adults in South Africa: multimethod evidence from a population-based longitudinal study
title_sort predictors of covid 19 vaccine uptake among adults in south africa multimethod evidence from a population based longitudinal study
url https://gh.bmj.com/content/8/8/e012433.full
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