Transfer functions linking neural calcium to single voxel functional ultrasound signal

Neurovascular coupling refers to changes in cerebral blood flow in response to neuronal stimulation, but to what extent this change can report neuronal activation is not known. Here the authors develop transfer functions between neural calcium signals and functional ultrasound changes in blood volum...

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Main Authors: Ali-Kemal Aydin, William D. Haselden, Yannick Goulam Houssen, Christophe Pouzat, Ravi L. Rungta, Charlie Demené, Mickael Tanter, Patrick J. Drew, Serge Charpak, Davide Boido
Format: Article
Language:English
Published: Nature Portfolio 2020-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-16774-9
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author Ali-Kemal Aydin
William D. Haselden
Yannick Goulam Houssen
Christophe Pouzat
Ravi L. Rungta
Charlie Demené
Mickael Tanter
Patrick J. Drew
Serge Charpak
Davide Boido
author_facet Ali-Kemal Aydin
William D. Haselden
Yannick Goulam Houssen
Christophe Pouzat
Ravi L. Rungta
Charlie Demené
Mickael Tanter
Patrick J. Drew
Serge Charpak
Davide Boido
author_sort Ali-Kemal Aydin
collection DOAJ
description Neurovascular coupling refers to changes in cerebral blood flow in response to neuronal stimulation, but to what extent this change can report neuronal activation is not known. Here the authors develop transfer functions between neural calcium signals and functional ultrasound changes in blood volume in co-registered single voxel brain volumes.
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spelling doaj.art-ca77cc2297bf43129c67c4233fb0779a2022-12-21T19:10:53ZengNature PortfolioNature Communications2041-17232020-06-0111111010.1038/s41467-020-16774-9Transfer functions linking neural calcium to single voxel functional ultrasound signalAli-Kemal Aydin0William D. Haselden1Yannick Goulam Houssen2Christophe Pouzat3Ravi L. Rungta4Charlie Demené5Mickael Tanter6Patrick J. Drew7Serge Charpak8Davide Boido9INSERM U1128, Laboratory of Neurophysiology and New Microscopy, Université de ParisMedical Scientist Training Program and Neuroscience Graduate Program, The Pennsylvania State UniversityINSERM U1128, Laboratory of Neurophysiology and New Microscopy, Université de ParisMAP5, Mathématiques Appliquées Paris 5, CNRS UMR 8145INSERM U1128, Laboratory of Neurophysiology and New Microscopy, Université de ParisPhysics for Medicine, ESPCI, INSERM, CNRS, PSL Research UniversityPhysics for Medicine, ESPCI, INSERM, CNRS, PSL Research UniversityDepartment of Engineering Science and Mechanics, The Pennsylvania State UniversityINSERM U1128, Laboratory of Neurophysiology and New Microscopy, Université de ParisINSERM U1128, Laboratory of Neurophysiology and New Microscopy, Université de ParisNeurovascular coupling refers to changes in cerebral blood flow in response to neuronal stimulation, but to what extent this change can report neuronal activation is not known. Here the authors develop transfer functions between neural calcium signals and functional ultrasound changes in blood volume in co-registered single voxel brain volumes.https://doi.org/10.1038/s41467-020-16774-9
spellingShingle Ali-Kemal Aydin
William D. Haselden
Yannick Goulam Houssen
Christophe Pouzat
Ravi L. Rungta
Charlie Demené
Mickael Tanter
Patrick J. Drew
Serge Charpak
Davide Boido
Transfer functions linking neural calcium to single voxel functional ultrasound signal
Nature Communications
title Transfer functions linking neural calcium to single voxel functional ultrasound signal
title_full Transfer functions linking neural calcium to single voxel functional ultrasound signal
title_fullStr Transfer functions linking neural calcium to single voxel functional ultrasound signal
title_full_unstemmed Transfer functions linking neural calcium to single voxel functional ultrasound signal
title_short Transfer functions linking neural calcium to single voxel functional ultrasound signal
title_sort transfer functions linking neural calcium to single voxel functional ultrasound signal
url https://doi.org/10.1038/s41467-020-16774-9
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