Oesophageal Manometry in Experimental Pigs: Methods and Initial Experience
The aim of this study project was to prepare our own method of porcine oesophageal manometry. Ten mature experimental pigs entered the study. Conventional water-perfused system was decided for manometry. Porcine resting and relaxed pressures of the lower oesophageal sphincter are fully comparable wi...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Karolinum Press
2016-03-01
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| Series: | Acta Medica |
| Subjects: | |
| Online Access: | http://actamedica.lfhk.cuni.cz/58/4/0131/ |
| Summary: | The aim of this study project was to prepare our own method of porcine oesophageal manometry. Ten mature experimental pigs entered the study. Conventional water-perfused system was decided for manometry. Porcine resting and relaxed pressures of the lower oesophageal sphincter are fully comparable with healthy human subjects. Evocable swallowing is doable and oesophageal peristalsis is quantifiable. Basic manometric parameters were different in male and female animals. Oesophageal manometry in experimental pigs is feasible. Porcine oesophageal manometry will be usable for preclinical studies in future. |
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| ISSN: | 1211-4286 1805-9694 |