The Impact of Brexit on the Pharmaceutical Supply Chain of the United Kingdom: Scoping Review Protocol
BackgroundThe continuing uncertainty around Brexit has caused concern in the pharmaceutical industry and among health care professionals and patients. The exact consequences of Brexit on the pharmaceutical supply chain in the United Kingdom will depend on whether a deal is reached and what it entail...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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JMIR Publications
2020-09-01
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| Series: | JMIR Research Protocols |
| Online Access: | http://www.researchprotocols.org/2020/9/e17684/ |
| _version_ | 1828937889976680448 |
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| author | Milne-Ives, Madison Lam, Ching van Velthoven, Michelle Meinert, Edward |
| author_facet | Milne-Ives, Madison Lam, Ching van Velthoven, Michelle Meinert, Edward |
| author_sort | Milne-Ives, Madison |
| collection | DOAJ |
| description | BackgroundThe continuing uncertainty around Brexit has caused concern in the pharmaceutical industry and among health care professionals and patients. The exact consequences of Brexit on the pharmaceutical supply chain in the United Kingdom will depend on whether a deal is reached and what it entails, but it is likely to be affected by the withdrawal of the United Kingdom from the European Union. Regulatory issues and delays in supply have the potential to negatively affect the ability of UK residents to receive an adequate and timely supply of necessary medicines.
ObjectiveThe purpose of this protocol is to provide an overview and critical analysis of current perspectives on the effect of Brexit on the UK pharmaceutical supply chain.
MethodsThe PRISMA-ScR (Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews) guidelines will be used to structure this protocol. A systematic search of MEDLINE, EMBASE, PsycINFO, Healthcare Management Information Consortium (HMIC), Cochrane, Web of Science, Business Source Complete, EconLit, and Economist Intelligence Unit will be conducted, as well as a Google and Nexis.UK search for grey literature such as reports, opinion pieces, and press releases. Two reviewers will independently screen the titles and abstracts of identified references and select studies according to the eligibility criteria. Any discrepancies will then be discussed and resolved. One reviewer will extract data from the included studies into a standardized form, which will be validated by a second reviewer. Risk of bias will be assessed using the Cochrane Collaboration Risk of Bias tool for any randomized controlled trials; quality will be assessed using the relevant Critical Appraisal Skills Programme (CASP) checklists; and grey literature will be assessed using the Authority, Accuracy, Coverage, Objectivity, Date, Significance (AACODS) checklist. Outcomes include the agreement between sources on the potential, likelihood, and severity of the consequences of Brexit on the UK pharmaceutical supply chain.
ResultsResults will be included in the scoping review, which will be published in 2020.
ConclusionsThis scoping review will summarize the currently expected consequences of Brexit on the UK pharmaceutical supply chain.
International Registered Report Identifier (IRRID)PRR1-10.2196/17684 |
| first_indexed | 2024-12-14T02:32:28Z |
| format | Article |
| id | doaj.art-ca79bba775c546db8412ff8553b6b5d1 |
| institution | Directory Open Access Journal |
| issn | 1929-0748 |
| language | English |
| last_indexed | 2024-12-14T02:32:28Z |
| publishDate | 2020-09-01 |
| publisher | JMIR Publications |
| record_format | Article |
| series | JMIR Research Protocols |
| spelling | doaj.art-ca79bba775c546db8412ff8553b6b5d12022-12-21T23:20:13ZengJMIR PublicationsJMIR Research Protocols1929-07482020-09-0199e1768410.2196/17684The Impact of Brexit on the Pharmaceutical Supply Chain of the United Kingdom: Scoping Review ProtocolMilne-Ives, MadisonLam, Chingvan Velthoven, MichelleMeinert, EdwardBackgroundThe continuing uncertainty around Brexit has caused concern in the pharmaceutical industry and among health care professionals and patients. The exact consequences of Brexit on the pharmaceutical supply chain in the United Kingdom will depend on whether a deal is reached and what it entails, but it is likely to be affected by the withdrawal of the United Kingdom from the European Union. Regulatory issues and delays in supply have the potential to negatively affect the ability of UK residents to receive an adequate and timely supply of necessary medicines. ObjectiveThe purpose of this protocol is to provide an overview and critical analysis of current perspectives on the effect of Brexit on the UK pharmaceutical supply chain. MethodsThe PRISMA-ScR (Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews) guidelines will be used to structure this protocol. A systematic search of MEDLINE, EMBASE, PsycINFO, Healthcare Management Information Consortium (HMIC), Cochrane, Web of Science, Business Source Complete, EconLit, and Economist Intelligence Unit will be conducted, as well as a Google and Nexis.UK search for grey literature such as reports, opinion pieces, and press releases. Two reviewers will independently screen the titles and abstracts of identified references and select studies according to the eligibility criteria. Any discrepancies will then be discussed and resolved. One reviewer will extract data from the included studies into a standardized form, which will be validated by a second reviewer. Risk of bias will be assessed using the Cochrane Collaboration Risk of Bias tool for any randomized controlled trials; quality will be assessed using the relevant Critical Appraisal Skills Programme (CASP) checklists; and grey literature will be assessed using the Authority, Accuracy, Coverage, Objectivity, Date, Significance (AACODS) checklist. Outcomes include the agreement between sources on the potential, likelihood, and severity of the consequences of Brexit on the UK pharmaceutical supply chain. ResultsResults will be included in the scoping review, which will be published in 2020. ConclusionsThis scoping review will summarize the currently expected consequences of Brexit on the UK pharmaceutical supply chain. International Registered Report Identifier (IRRID)PRR1-10.2196/17684http://www.researchprotocols.org/2020/9/e17684/ |
| spellingShingle | Milne-Ives, Madison Lam, Ching van Velthoven, Michelle Meinert, Edward The Impact of Brexit on the Pharmaceutical Supply Chain of the United Kingdom: Scoping Review Protocol JMIR Research Protocols |
| title | The Impact of Brexit on the Pharmaceutical Supply Chain of the United Kingdom: Scoping Review Protocol |
| title_full | The Impact of Brexit on the Pharmaceutical Supply Chain of the United Kingdom: Scoping Review Protocol |
| title_fullStr | The Impact of Brexit on the Pharmaceutical Supply Chain of the United Kingdom: Scoping Review Protocol |
| title_full_unstemmed | The Impact of Brexit on the Pharmaceutical Supply Chain of the United Kingdom: Scoping Review Protocol |
| title_short | The Impact of Brexit on the Pharmaceutical Supply Chain of the United Kingdom: Scoping Review Protocol |
| title_sort | impact of brexit on the pharmaceutical supply chain of the united kingdom scoping review protocol |
| url | http://www.researchprotocols.org/2020/9/e17684/ |
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