Cancer-Related Alopecia: From Etiologies to Global Management
Alopecia represents a multifaceted challenge with distinct etiologies and consequences. Transposed to the world of oncology, different types of alopecia and molecular pathways have been characterized, allowing a better understanding of the underlying mechanisms. In patients with cancer, alopecia can...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-11-01
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| Series: | Cancers |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2072-6694/13/21/5556 |
| _version_ | 1797512737888141312 |
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| author | Stanislas Quesada Alexandre Guichard Frédéric Fiteni |
| author_facet | Stanislas Quesada Alexandre Guichard Frédéric Fiteni |
| author_sort | Stanislas Quesada |
| collection | DOAJ |
| description | Alopecia represents a multifaceted challenge with distinct etiologies and consequences. Transposed to the world of oncology, different types of alopecia and molecular pathways have been characterized, allowing a better understanding of the underlying mechanisms. In patients with cancer, alopecia can be iatrogenic (i.e., due to conventional chemotherapies, endocrine therapies, targeted therapies, immunotherapies, radiotherapy and surgery) or a direct consequence of the disease itself (e.g., malnutrition, scalp metastases and paraneoplastic syndromes). Identification of the actual incriminated mechanism(s) is therefore essential in order to deliver appropriate supportive care, whether preventive or curative. On the preventive side, the last few years have seen the advent of the automated cooling cap, a prophylactic approach supported by several randomized clinical trials. On the curative side, although the treatments currently available are limited, several promising therapeutic approaches are under development. Appropriate alopecia management is essential, particularly regarding its psychological repercussions with significant consequences on the quality of life of patients and their family and with a potential impact on treatment compliance. |
| first_indexed | 2024-03-10T06:04:59Z |
| format | Article |
| id | doaj.art-ca7a4a04910f4fc784e0497b269bd1aa |
| institution | Directory Open Access Journal |
| issn | 2072-6694 |
| language | English |
| last_indexed | 2024-03-10T06:04:59Z |
| publishDate | 2021-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cancers |
| spelling | doaj.art-ca7a4a04910f4fc784e0497b269bd1aa2023-11-22T20:36:58ZengMDPI AGCancers2072-66942021-11-011321555610.3390/cancers13215556Cancer-Related Alopecia: From Etiologies to Global ManagementStanislas Quesada0Alexandre Guichard1Frédéric Fiteni2Institut Régional du Cancer de Montpellier, 34090 Montpellier, FranceLegacy Healthcare Switzerland SA, 1066 Epalinges, SwitzerlandMedical Oncology Department, University Hospital, 30900 Nîmes, FranceAlopecia represents a multifaceted challenge with distinct etiologies and consequences. Transposed to the world of oncology, different types of alopecia and molecular pathways have been characterized, allowing a better understanding of the underlying mechanisms. In patients with cancer, alopecia can be iatrogenic (i.e., due to conventional chemotherapies, endocrine therapies, targeted therapies, immunotherapies, radiotherapy and surgery) or a direct consequence of the disease itself (e.g., malnutrition, scalp metastases and paraneoplastic syndromes). Identification of the actual incriminated mechanism(s) is therefore essential in order to deliver appropriate supportive care, whether preventive or curative. On the preventive side, the last few years have seen the advent of the automated cooling cap, a prophylactic approach supported by several randomized clinical trials. On the curative side, although the treatments currently available are limited, several promising therapeutic approaches are under development. Appropriate alopecia management is essential, particularly regarding its psychological repercussions with significant consequences on the quality of life of patients and their family and with a potential impact on treatment compliance.https://www.mdpi.com/2072-6694/13/21/5556alopeciasupportive carepsycho-oncologyquality of life |
| spellingShingle | Stanislas Quesada Alexandre Guichard Frédéric Fiteni Cancer-Related Alopecia: From Etiologies to Global Management Cancers alopecia supportive care psycho-oncology quality of life |
| title | Cancer-Related Alopecia: From Etiologies to Global Management |
| title_full | Cancer-Related Alopecia: From Etiologies to Global Management |
| title_fullStr | Cancer-Related Alopecia: From Etiologies to Global Management |
| title_full_unstemmed | Cancer-Related Alopecia: From Etiologies to Global Management |
| title_short | Cancer-Related Alopecia: From Etiologies to Global Management |
| title_sort | cancer related alopecia from etiologies to global management |
| topic | alopecia supportive care psycho-oncology quality of life |
| url | https://www.mdpi.com/2072-6694/13/21/5556 |
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