Regulation of the Sae Two-Component System by Branched-Chain Fatty Acids in Staphylococcus aureus

Regulation of the Sae Two-Component System by Branched-Chain Fatty Acids in Staphylococcus aureus

ABSTRACT Staphylococcus aureus is a ubiquitous Gram-positive bacterium and an opportunistic human pathogen. S. aureus pathogenesis relies on a complex network of regulatory factors that adjust gene expression. Two important factors in this network are CodY, a repressor protein responsive to nutrient...

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Bibliographic Details
Main Authors: Augustus Pendleton, Won-Sik Yeo, Shahad Alqahtani, Dennis A. DiMaggio, Carl J. Stone, Zhaotao Li, Vineet K. Singh, Christopher P. Montgomery, Taeok Bae, Shaun R. Brinsmade
Format: Article
Language:English
Published: American Society for Microbiology 2022-10-01
Series:mBio
Subjects:
MRSA
Staphylococcus aureus
SaeRS
virulence
membrane
branched-chain fatty acids
Online Access:https://journals.asm.org/doi/10.1128/mbio.01472-22

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