Pharmacological Evaluation of LiuWei Zhuanggu Granules in Rats
Many commonly consumed foods, herbs and spices contain a complex array of naturally occurring bioactive molecules called phytochemicals, which may confer health benefits. In this study, the impact of LiuWei Zhuanggu Granules (LWZGG) on mineral metabolism in osteopenia development was evaluated. Resu...
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| Format: | Article |
| Language: | English |
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MDPI AG
2012-07-01
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| Series: | Molecules |
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| Online Access: | http://www.mdpi.com/1420-3049/17/7/8001 |
| _version_ | 1828337311747670016 |
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| author | Haiming Zhu Liang Ding Haijun Xiao Weifeng Ni Feng Xue Zhiming He |
| author_facet | Haiming Zhu Liang Ding Haijun Xiao Weifeng Ni Feng Xue Zhiming He |
| author_sort | Haiming Zhu |
| collection | DOAJ |
| description | Many commonly consumed foods, herbs and spices contain a complex array of naturally occurring bioactive molecules called phytochemicals, which may confer health benefits. In this study, the impact of LiuWei Zhuanggu Granules (LWZGG) on mineral metabolism in osteopenia development was evaluated. Results showed that serum estrogen, bone gla protein (BGP), and calcitonin (CT) levels, bone Ca, Zn and Cu levels, femur, lumbar vertebrae and trabecular bone density, tibia maximum stress and maximum bending strength were increased, and serum parathyroid hormone (PTH), serum and urine Ca, Zn and Cu levels were decreased in rat bone. It can be concluded that LWZGG is useful to improve bone quality in ovariectomized (OVX) rats. |
| first_indexed | 2024-04-13T22:13:43Z |
| format | Article |
| id | doaj.art-ca8463342f9d4fca9f8a1a91500f1dcf |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-04-13T22:13:43Z |
| publishDate | 2012-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-ca8463342f9d4fca9f8a1a91500f1dcf2022-12-22T02:27:38ZengMDPI AGMolecules1420-30492012-07-011778001800910.3390/molecules17078001Pharmacological Evaluation of LiuWei Zhuanggu Granules in RatsHaiming ZhuLiang DingHaijun XiaoWeifeng NiFeng XueZhiming HeMany commonly consumed foods, herbs and spices contain a complex array of naturally occurring bioactive molecules called phytochemicals, which may confer health benefits. In this study, the impact of LiuWei Zhuanggu Granules (LWZGG) on mineral metabolism in osteopenia development was evaluated. Results showed that serum estrogen, bone gla protein (BGP), and calcitonin (CT) levels, bone Ca, Zn and Cu levels, femur, lumbar vertebrae and trabecular bone density, tibia maximum stress and maximum bending strength were increased, and serum parathyroid hormone (PTH), serum and urine Ca, Zn and Cu levels were decreased in rat bone. It can be concluded that LWZGG is useful to improve bone quality in ovariectomized (OVX) rats.http://www.mdpi.com/1420-3049/17/7/8001LWZGGCaZn, CuCTBGPuterine |
| spellingShingle | Haiming Zhu Liang Ding Haijun Xiao Weifeng Ni Feng Xue Zhiming He Pharmacological Evaluation of LiuWei Zhuanggu Granules in Rats Molecules LWZGG Ca Zn, Cu CT BGP uterine |
| title | Pharmacological Evaluation of LiuWei Zhuanggu Granules in Rats |
| title_full | Pharmacological Evaluation of LiuWei Zhuanggu Granules in Rats |
| title_fullStr | Pharmacological Evaluation of LiuWei Zhuanggu Granules in Rats |
| title_full_unstemmed | Pharmacological Evaluation of LiuWei Zhuanggu Granules in Rats |
| title_short | Pharmacological Evaluation of LiuWei Zhuanggu Granules in Rats |
| title_sort | pharmacological evaluation of liuwei zhuanggu granules in rats |
| topic | LWZGG Ca Zn, Cu CT BGP uterine |
| url | http://www.mdpi.com/1420-3049/17/7/8001 |
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