The architecture of the Schizosaccharomyces pombe CCR4-NOT complex
CCR4-NOT is a protein complex involved in a variety of important genetic processes. Here, the authors report the mid-resolution structure of this complex, and model the positions and contacts between the subunits, providing structural support for the previously reported functions of the complex.
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2016-01-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/ncomms10433 |
| _version_ | 1818419745801633792 |
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| author | Marta Ukleja Jorge Cuellar Aleksandra Siwaszek Joanna M. Kasprzak Mariusz Czarnocki-Cieciura Janusz M. Bujnicki Andrzej Dziembowski Jose M. Valpuesta |
| author_facet | Marta Ukleja Jorge Cuellar Aleksandra Siwaszek Joanna M. Kasprzak Mariusz Czarnocki-Cieciura Janusz M. Bujnicki Andrzej Dziembowski Jose M. Valpuesta |
| author_sort | Marta Ukleja |
| collection | DOAJ |
| description | CCR4-NOT is a protein complex involved in a variety of important genetic processes. Here, the authors report the mid-resolution structure of this complex, and model the positions and contacts between the subunits, providing structural support for the previously reported functions of the complex. |
| first_indexed | 2024-12-14T12:43:27Z |
| format | Article |
| id | doaj.art-ca87b36036974eccbfea1dd84b813505 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-14T12:43:27Z |
| publishDate | 2016-01-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-ca87b36036974eccbfea1dd84b8135052022-12-21T23:00:50ZengNature PortfolioNature Communications2041-17232016-01-017111110.1038/ncomms10433The architecture of the Schizosaccharomyces pombe CCR4-NOT complexMarta Ukleja0Jorge Cuellar1Aleksandra Siwaszek2Joanna M. Kasprzak3Mariusz Czarnocki-Cieciura4Janusz M. Bujnicki5Andrzej Dziembowski6Jose M. Valpuesta7Institute of Biochemistry and Biophysics, Polish Academy of SciencesDepartment of Structure of Macromolecules, Centro Nacional de Biotecnología (CNB-CSIC)Institute of Biochemistry and Biophysics, Polish Academy of SciencesLaboratory of Bioinformatics and Protein Engineering, International Institute of Molecular and Cell Biology in WarsawInstitute of Biochemistry and Biophysics, Polish Academy of SciencesLaboratory of Bioinformatics and Protein Engineering, International Institute of Molecular and Cell Biology in WarsawInstitute of Biochemistry and Biophysics, Polish Academy of SciencesDepartment of Structure of Macromolecules, Centro Nacional de Biotecnología (CNB-CSIC)CCR4-NOT is a protein complex involved in a variety of important genetic processes. Here, the authors report the mid-resolution structure of this complex, and model the positions and contacts between the subunits, providing structural support for the previously reported functions of the complex.https://doi.org/10.1038/ncomms10433 |
| spellingShingle | Marta Ukleja Jorge Cuellar Aleksandra Siwaszek Joanna M. Kasprzak Mariusz Czarnocki-Cieciura Janusz M. Bujnicki Andrzej Dziembowski Jose M. Valpuesta The architecture of the Schizosaccharomyces pombe CCR4-NOT complex Nature Communications |
| title | The architecture of the Schizosaccharomyces pombe CCR4-NOT complex |
| title_full | The architecture of the Schizosaccharomyces pombe CCR4-NOT complex |
| title_fullStr | The architecture of the Schizosaccharomyces pombe CCR4-NOT complex |
| title_full_unstemmed | The architecture of the Schizosaccharomyces pombe CCR4-NOT complex |
| title_short | The architecture of the Schizosaccharomyces pombe CCR4-NOT complex |
| title_sort | architecture of the schizosaccharomyces pombe ccr4 not complex |
| url | https://doi.org/10.1038/ncomms10433 |
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