Characterization of Bacillus anthracis Spore Proteins Using a Nanoscaffold Vaccine Platform

Characterization of Bacillus anthracis Spore Proteins Using a Nanoscaffold Vaccine Platform

Subunit vaccines are theoretically safe and easy to manufacture but require effective adjuvants and delivery systems to yield protective immunity, particularly at critical mucosal sites such as the lung. We investigated nanolipoprotein particles (NLPs) containing the Toll-like receptor 4 agonist mon...

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Bibliographic Details
Main Authors: Dina R. Weilhammer, Alexis D. Dunkle, Tyler Boone, Sean F. Gilmore, Mark Khemmani, Sandra K. G. Peters, Paul D. Hoeprich, Nicholas O. Fischer, Craig D. Blanchette, Adam Driks, Amy Rasley
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Immunology
Subjects:
nanoscaffold
nanolipoprotein particle (NLP)
vaccine
spore antigens
anthrax
monophosphoryl lipid A (MPLA)
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01264/full

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